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Significant cohort of non-alcoholic fatty liver disease with portal vein thrombosis in transplant waiting list.

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dc.contributor.authorSenturk, H
dc.contributor.authorBasaranoglu, METİN
dc.contributor.authorNajjar, SM
dc.contributor.authorDemirbag, AE
dc.contributor.institutionauthorBAŞARANOĞLU, METİN
dc.contributor.institutionauthorŞENTÜRK, HAKAN
dc.date.accessioned2020-01-22T20:59:36Z
dc.date.available2020-01-22T20:59:36Z
dc.date.issued2016-03-08T00:00:00Z
dc.description.abstractAim: To characterize non-alcoholic fatty liver disease (NAFLD) presentation with esophageal varices. Methods: We carried out a retrospective cohort study on 258 patients with esophageal varices at a single tertiary referral center. These patients underwent diagnosis of several liver diseases, including: NAFLD-associated cirrhosis, hepatitis B, hepatitis C, Wilson disease, autoimune liver diseases, and others. Results: Of the 258 patients, 39% of patients exhibited esophageal varices due to NAFLD-associated cirrhosis. Of the 38 (14.7%) patients developed hepatocellular carcinoma during follow-up, 52% were due to hepatitis B, 26% due to hepatitis C and 13.2% due to NAFLD. Of the 258 patients, 50.0% with NAFLD, 33.3% with hepatitis B, 26.3% with hepatitis C, and 58.3% with other diseases were alive at the end of the 5-year period with a significant difference according to the Kaplan-Meier log Rank test (P = 0.040). Portal vein thrombosis was detected in 47.5% of patients with NAFLD, in 29% of patients with hepatitis B, in 17% of patients with hepatitis C, and in 62% of patients with other related diseases (P < 0.0001). Conclusion: Our study showed a proportionally greater elevation in liver transplant candidacy in patients with NAFLD and portal vein thrombosis. Older patients were more prone to developing cirrhosis, hepatocellular carcinoma and a high mortality rate. However, younger patients exhibited more portal vein thrombosis and gastric varices.en
dc.identifier.citationBasaranoglu M., Najjar S., Demirbag A., Senturk H., -Significant cohort of non-alcoholic fatty liver disease with portal vein thrombosis in transplant waiting list.-, World journal of hepatology, cilt.8, ss.376-84, 2016
dc.identifier.doi10.4254/wjh.v8.i7.376
dc.identifier.pubmed26981175
dc.identifier.scopus84959900252
dc.identifier.trdizintrdizin
dc.identifier.urihttps://openaccess.bezmialem.edu.tr/handle/20.500.12645/13479
dc.identifier.wosWOS:000439231600004
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleSignificant cohort of non-alcoholic fatty liver disease with portal vein thrombosis in transplant waiting list.
dc.typeArticle
dspace.entity.typePublication
local.avesis.id8b26c21a-bf11-4d4d-abf4-e7d5beb1f6ec
local.publication.isinternational1
relation.isAuthorOfPublication8a7b20a3-6e3e-4a44-acbf-16854071f233
relation.isAuthorOfPublication278fcf63-3b92-4368-bff6-f140ebd9aeb3
relation.isAuthorOfPublication.latestForDiscovery278fcf63-3b92-4368-bff6-f140ebd9aeb3
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