Publication: Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes
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Date
2014-04-01T00:00:00Z
Institution Authors
Authors
Yeo, Adeline S. L.
Azhar, Nur Atiqah
Yeow, Wanyi
Talbot, C. Conover
Khan, MOHAMMAD ASİF
Shankar, Esaki M.
Rathakrishnan, Anusyah
Azizan, Azliyati
Wang, Seok Mui
Lee, Siew Kim
Journal Title
Journal ISSN
Volume Title
Publisher
Metrikler
Abstract
Objectives: Dengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, asymptomatic dengue remains largely unnoticed. Therefore, we sought to investigate the immune correlates conferring protection to individuals that remain clinically asymptomatic.
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Citation
Yeo A. S. L. , Azhar N. A. , Yeow W., Talbot C. C. , Khan M. A. , Shankar E. M. , Rathakrishnan A., Azizan A., Wang S. M. , Lee S. K. , et al., -Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes-, PLOS ONE, cilt.9, sa.4, 2014