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GENOTYPING AND ANALYSIS OF rs7501939 POLYMORPHISM FOR PROSTATE CANCER

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dc.contributor.authorOzkan, Ebru
dc.contributor.authorERDEMİR ÜSTÜNDAĞ, Ayşegül
dc.contributor.authorTorer, Bugra Dogukan
dc.contributor.authorTasci, Ali Ihsan
dc.contributor.authorBASKIN, YASEMİN
dc.contributor.authorELLİDOKUZ, HÜLYA
dc.contributor.authorBALIK, Dilek
dc.date.accessioned2020-10-22T21:41:01Z
dc.date.available2020-10-22T21:41:01Z
dc.date.issued2015-12-01T00:00:00Z
dc.description.abstractProstate cancer is the second most common cause of death from cancer among men in Turkey. It is known that genetics plays a critical role in prostate cancer susceptibility. Several genome wide association studies reported that rs7501939 polymorphism was significantly associated with prostate cancer. To confirm association of rs7501939 alleles with prostate cancer in our population, genotyping was conducted by using the iPLEX assay in study group which consists of 85 prostate cancer patients and 90 healty controls. In this study, previous reports of rs7501939 variant association with prostate cancer was not confirmed for our population. The odds ratio for prostate cancer was 0,75 (95% CI=0,48-1,18) for carriers of any T allele compared with noncarriers (p=0,211). Chi square and Fisher-s exact test results showed that rs7501939 variant was not statistically associated with clinico-pathological variables of prostate cancer patients in our population.
dc.identifier.citationOzkan E., ERDEMİR ÜSTÜNDAĞ A., Torer B. D. , Tasci A. I. , BASKIN Y., ELLİDOKUZ H., BALIK D., -GENOTYPING AND ANALYSIS OF rs7501939 POLYMORPHISM FOR PROSTATE CANCER-, SIGMA JOURNAL OF ENGINEERING AND NATURAL SCIENCES-SIGMA MUHENDISLIK VE FEN BILIMLERI DERGISI, cilt.6, ss.101-107, 2015
dc.identifier.trdizintrdizin
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24988
dc.identifier.wosWOS:000219705700009
dc.subjectProstate cancer
dc.titleGENOTYPING AND ANALYSIS OF rs7501939 POLYMORPHISM FOR PROSTATE CANCER
dc.typeArticle
dspace.entity.typePublication
local.avesis.idfe14fd97-6b11-4ae3-bd52-6e23caac7276
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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