Publication:
Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing beta-lactamases in Pseudomonas aeruginosa in Turkey

Simple item page
dc.contributor.authorÇOPUR ÇİÇEK, AYŞEGÜL
dc.contributor.authorDuzgun, Azer Ozad
dc.contributor.authorBonnin, Remy A.
dc.contributor.authorCeylan, Aysenur
dc.contributor.authorSaral, Aysegul
dc.contributor.authorNordmann, Patrice
dc.contributor.authorSandalli, Cemal
dc.date.accessioned2020-10-22T18:59:37Z
dc.date.available2020-10-22T18:59:37Z
dc.date.issued2014-03-01T00:00:00Z
dc.description.abstractPseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), extensively-drug resistant (n = 5), or pan-drug resistant (n = I). PCR and DNA sequence analysis revealed that 1 strain possessed the bla(GES-5) and another carried a novel bla(VIM) variant, named VIM-38. This new gene exhibited 1 amino acid substitution (Ala265Val) in comparison to its closest variant, VIM-5. Both VIM encoding genes were clones and demonstrated similar susceptibility profile when expressed in identical background. The presence of VIM-38 increases the diversity of carbapenemases in Turkey. (C) 2014 Elsevier Inc. All rights reserved.
dc.identifier.citationIraz M., Duzgun A. O. , ÇOPUR ÇİÇEK A., Bonnin R. A. , Ceylan A., Saral A., Nordmann P., Sandalli C., -Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing beta-lactamases in Pseudomonas aeruginosa in Turkey-, DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, cilt.78, ss.292-294, 2014
dc.identifier.doi10.1016/j.diagmicrobio.2013.12.003
dc.identifier.pubmed24428980
dc.identifier.scopus84893745009
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24403
dc.identifier.wosWOS:000332056500018
dc.titleCharacterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing beta-lactamases in Pseudomonas aeruginosa in Turkey
dc.typeArticle
dspace.entity.typePublication
local.avesis.idab73e785-db8a-44b9-9664-8d7b6e32b175
local.publication.isinternational1
Files
Collections
Yayınlar - Eserler