Publication:
Utilization of Wilms- tumor 1 antigen in a panel for differential diagnosis of ovarian carcinomas

dc.contributor.authorSen, Dilek Sakirahmet
dc.contributor.authorKarasu, AYŞE FİLİZ
dc.contributor.authorGecer, Melin Ozgun
dc.contributor.authorKARADAYI, Nimet
dc.contributor.authorYamuc, Elif Ablan
dc.contributor.institutionauthorGÖKMEN KARASU, AYŞE FİLİZ
dc.date.accessioned2019-10-05T21:52:52Z
dc.date.available2019-10-05T21:52:52Z
dc.date.issued2016-03-01
dc.description.abstractObjective: Ovarian metasteses are often mistaken for primary adenocarcinoma. Studies conducted in recent years have focused on a search for an immunohistochemical marker to aid the differential diagnosis primary and metastatic ovarian carcinoma. Our study objective was to study the usefulness of Wilms tumor 1 (WT 1) antigen in this context. Materials and methods: The study was conducted at the pathology clinic of Lütfi Kırdar Training and Research Hospital. Deparaffinated blocks of 40 epithelial ovarian tumors, 40 colon adenocarcinomas, and 35 cases of omentum metastases were studied. Cytokeratin 7 (CK 7), cytokeratin 20 (CK 20), and WT 1 were applied to all specimens. Results: All ovarian adenocarcinomas were stained with CK 7 (100%). Colorectal adenocarcinomas were stained positive with CK 20 in 87.5% of cases. Primary ovarian adenocarcinomas stained positive with WT 1 in 82.5% of the cases and none of the colorectal adenocarcinomas showed staining with WT 1 (0%). Conclusion: WT 1 can be used in conjuction with CK 7 in the differential diagnosis of ovarian carcinomas.en
dc.identifier10.1007/bf01105782
dc.identifier.citationSen D. S. , Karasu A. F. , Gecer M. O. , KARADAYI N., Yamuc E. A. , -Utilization of Wilms- tumor 1 antigen in a panel for differential diagnosis of ovarian carcinomas-, TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.13, ss.37-41, 2016
dc.identifier.doi10.4274/tjod.22220
dc.identifier.pubmed28913087
dc.identifier.scopus84964507844
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/8351
dc.identifier.wosWOS:000376597400010
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleUtilization of Wilms- tumor 1 antigen in a panel for differential diagnosis of ovarian carcinomas
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameNeurosurgical review
local.avesis.idcfe2a28b-580f-437a-b313-5e23c9760018
local.avesis.response8227
local.publication.isinternational1
relation.isAuthorOfPublication64cd0679-6c73-402a-b6f8-d1ed23d953ea
relation.isAuthorOfPublication.latestForDiscovery64cd0679-6c73-402a-b6f8-d1ed23d953ea
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