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The relationship between Willis-Ekbom disease and serum ferritin levels among children in Northwestern Turkey

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dc.contributor.authorHALAC, Gulistan
dc.contributor.authorSEZER, Gulsen M.
dc.contributor.authorSAGLAM, Neslihan O.
dc.contributor.authorTekturk, Pinar
dc.contributor.authorDEMIR, Aysegul D.
dc.contributor.authorDEMIR, Saliha
dc.contributor.authorAKCAY, Faruk
dc.contributor.authorUSLU, Aysegul
dc.contributor.authorYapici, Zuhal
dc.contributor.authorAsil, TALİP
dc.contributor.institutionauthorASİL, TALIP
dc.date.accessioned2019-10-05T23:12:03Z
dc.date.available2019-10-05T23:12:03Z
dc.date.issued2015-10-01
dc.description.abstractObjective: To examine the incidence of restless legs syndrome (RLS) among children with iron deficiency, or iron deficiency anemia, or both, and the relationship between RLS prevalence and serum ferritin levels. Methods: This prospective, cross-sectional, case controlled study was carried out between January and June 2013, and included 98 iron deficiency and/or Neurosciences 2015; Vol. 20 (4) iron deficiency anemia, and 102 healthy children referred to the Neurology and Pediatric Departments of the Medical Faculty of Bezmialem Vakif University, Istanbul, Turkey. Both groups were evaluated according to the International Restless Legs Syndrome Study Group diagnostic criteria. Results: The range of ferritin levels was 0.01-12 mg/ ml in patients while it was 12.3-91.8 mg/mL in the control group. Restless legs syndrome was detected in 61.2% of children with iron deficiency anemia, and in 37.3% of children with normal biochemistry values. A statistically significant correlation was found between serum ferritin levels and frequency of RLS. In patients with serum ferritin levels higher than 50 ng/ml, 92.3% had no RLS, while 55.2% of patients with serum ferritin levels lower than 50ng/ ml had RLS. The patients with serum ferritin levels of >50ng/ml had a significantly higher incidence of RLS. Serum ferritin levels were significantly different between the 2 groups. Conclusion: The incidence of RLS, also known as Willis-Ekbom Disease, is high in children aged between 8-18 years with iron deficiency, or iron deficiency anemia, or both. This finding supports the importance of iron replacement therapy especially during the growth and development of children.en
dc.identifier10.1016/j.anl.2011.05.008
dc.identifier.citationHALAC G., SEZER G. M. , SAGLAM N. O. , Tekturk P., DEMIR A. D. , DEMIR S., AKCAY F., USLU A., Yapici Z., Asil T., -The relationship between Willis-Ekbom disease and serum ferritin levels among children in Northwestern Turkey-, NEUROSCIENCES, cilt.20, ss.336-340, 2015
dc.identifier.doi10.17712/nsj.2015.4.20150268
dc.identifier.pubmed26492111
dc.identifier.scopus84945301421
dc.identifier.urihttps://hdl.handle.net/20.500.12645/9680
dc.identifier.wosWOS:000367205900002
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleThe relationship between Willis-Ekbom disease and serum ferritin levels among children in Northwestern Turkey
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameAURIS NASUS LARYNX
local.avesis.idf134b719-9806-4f31-a19a-743ddfd9f7da
local.avesis.response9554
local.publication.isinternational1
relation.isAuthorOfPublicationd6d2b335-cf30-4de8-b2c6-9d158f661759
relation.isAuthorOfPublication.latestForDiscoveryd6d2b335-cf30-4de8-b2c6-9d158f661759
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