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Farklı Cerrahi Flep Geciktirme Yöntemlerinin Etkinliği ve Sistemik Toksisiteleri

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dc.contributor.authorKirazoğlu A.
dc.contributor.authorMirapoğlu S. L.
dc.contributor.authorKılıç Ü.
dc.contributor.authorGüneren E.
dc.contributor.authorSağır H. Ö.
dc.contributor.authorKoçyiğit A.
dc.contributor.authorYeşiloğlu N.
dc.contributor.authorCanter H. İ.
dc.contributor.authorÇay A.
dc.contributor.authorYıldız K.
dc.contributor.institutionauthorKİRAZOĞLU, AHMET
dc.contributor.institutionauthorGÜNEREN, ETHEM
dc.contributor.institutionauthorKOÇYİĞİT, ABDÜRRAHİM
dc.contributor.institutionauthorYILDIZ, KEMALETTİN
dc.date.accessioned2023-01-08T22:54:11Z
dc.date.available2023-01-08T22:54:11Z
dc.date.issued2022-05-25
dc.description.abstractIntroduction: The surgical flap delaying has been shown to be effective in preventing partial flap loss or in preparing larger flaps. However, there is no gold standard flap delay method in the literature. In this study, the authors aimed to compare 3 types of surgical delay methods to determine which model would increase more flap survival. The authors also investigated the effect of delay methods on circulating mononuclear leukocytes as a parameter of DNA damage. Materials and Methods: Twenty-four Sprague-Dawley male rats were divided into 4 groups. All subjects had a 10 × 3 cm modified McFarlane flap. Surface area measurements, biopsies, and blood samples were taken on the day of sacrification; 7th day for the control group and 14th day for delay groups. Results: Between incisional surgery delay groups, a significant difference was found in necrosis and apoptosis in the bipedicled group, and only necrosis in the tripedicled group compared to the control. In terms of DNA damage, it was found higher in all experimental groups than in the control group. Conclusions: Both incisional surgical delay procedures’ results were meaningfully effective when only incisions were made without the elevation of flaps. In conclusion, bipedicled incisional surgical delay seems to be the most effective method in McFarlane experimental flap model whereas two-staged surgeries may increase the risk of systemic toxicity
dc.identifier.citationKirazoğlu A., Mirapoğlu S. L., Kılıç Ü., Güneren E., Sağır H. Ö., Koçyiğit A., Yeşiloğlu N., Canter H. İ., Çay A., Yıldız K., \"Farklı Cerrahi Flep Geciktirme Yöntemlerinin Etkinliği ve Sistemik Toksisiteleri\", 10th EURAPS Research Council Meeting, Naples, İtalya, 25 - 26 Mayıs 2022, ss.73
dc.identifier.urihttps://hdl.handle.net/20.500.12645/34866
dc.relation.ispartof10th EURAPS Research Council Meeting
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectPlastik ve Rekonstriktif Cerrahi
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectPlastic and Reconstructive Surgery
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCERRAHİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectSURGERY
dc.subjectCerrahi
dc.subjectSurgery
dc.titleFarklı Cerrahi Flep Geciktirme Yöntemlerinin Etkinliği ve Sistemik Toksisiteleri
dc.typeconferenceObject
dspace.entity.typePublication
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