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Synthesis of new derivatives of 1-(3-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid

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2010-01-01T00:00:00Z
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Kasimogullari, Rahmi
Zengin, BELMA
Maden, Makbule
Mert, Samet
KAZAZ, Cavit
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Abstract
1-(3-Aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid (1) was synthesized according to the literature.(1) 2-(3-Aminophenyl)-2,6-dihydro-3,4-diphenyl-7H-pyrazolo[3,4-d]pyridazin-7-one (5) was obtained by the cyclocondensation reaction of 1 with hydrazine hydrate. New pyrazole derivatives of compounds 1 and 5 were synthesized by their reaction with beta-diketones, beta-ketoesters, beta-naphthol, phenol and various other reagents. The structures of the synthesized compounds were characterized by (1)H-NMR, (13)C-NMR, IR and mass spectroscopy, as well as elemental analysis.
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Kasimogullari R., Zengin B., Maden M., Mert S., KAZAZ C., -Synthesis of new derivatives of 1-(3-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid-, JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, cilt.75, ss.1625-1635, 2010
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