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Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs-s phosphorylation

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Date
2017-07-12T00:00:00Z
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Balkan, Irem Atay
Akulke, Ayca Zeynep Ilter
Bagatur, Yesim
Telci, Dilek
Goren, AHMET CEYHAN
Kirmizibekmez, Hasan
Yesilada, Erdem
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Abstract
Ethnopharmacological relevance: The leaves of Sambucus ebulus L. (Adoxaceae) are widely used in Turkish folk medicine particularly against inflammatory disorders. The fresh leaves after wilted over fire or the poultices prepared are directly applied externally to heal burns, edema, eczema, urticarial and abscess. Two iridoids were recently isolated (sambulin A, sambulin B) from the leaves of S. ebulus.
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Balkan I. A. , Akulke A. Z. I. , Bagatur Y., Telci D., Goren A. C. , Kirmizibekmez H., Yesilada E., -Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs-s phosphorylation-, JOURNAL OF ETHNOPHARMACOLOGY, cilt.206, ss.347-352, 2017
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http://hdl.handle.net/20.500.12645/25266
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