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Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy.

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dc.contributor.authorIDIZ, O
dc.contributor.authorAysan, E
dc.contributor.authorFIRAT, D
dc.contributor.authorERSOY, YELİZ EMİNE
dc.contributor.authorCENGIZ, MB
dc.contributor.authorAKBULUT, H
dc.contributor.authorISıK, A
dc.contributor.authorMUSLUMANOGLU, M
dc.contributor.institutionauthorAYŞAN, MUSTAFA ERHAN
dc.contributor.institutionauthorERSOY, YELIZ EMINE
dc.date.accessioned2019-10-05T13:40:23Z
dc.date.available2019-10-05T13:40:23Z
dc.date.issued2014-06-28
dc.description.abstractWe evaluated the effects of local flax seed oil and glycerol application for reducing adhesion formation after thyroidectomy. Material/Method: We randomly assigned 18 female Wistar albino rats (median weight: 275 g, median age: 4.5 mth) to 3 groups: 0.1 ml 0.9% NaCl, glycerol, and flax seed oil were sprayed in a perithyroidal area after thyroidectomy operation on all animals as anti-adhesive barriers. Rats were sacrificed on the postoperative 14th day and adhesions were evaluated macroscopically and microscopically. Results: The median macroscopic adhesion score was 3.0±0.0 in the 0.9% NaCl group, 1.33±0.52 in the glycerol group, and 1.67±0.53 in the flax seed oil group. The median histopathological fibrosis scores were 2.33±0.82, 0.67±0.52, and 0.83±0.75, respectively. Both glycerol and flaxseed oil group macroscopic and microscopic scores were significantly lower than the 0.9% NaCl group (p<0.05). There was no significant difference among the groups (p>0.05). Conclusions: Glycerol and flax seed oil both decrease the incidence of post-thyroidectomy adhesion in rats, but glycerol is more effective.en
dc.identifier10.1097/inf.0b013e31822bf4f6
dc.identifier.citationIDIZ O., Aysan E., FIRAT D., ERSOY Y. E. , CENGIZ M., AKBULUT H., ISıK A., MUSLUMANOGLU M., -Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy.-, Medical science monitor : international medical journal of experimental and clinical research, cilt.20, ss.1090-4, 2014
dc.identifier.doi10.12659/msm.890460
dc.identifier.pubmed24973306
dc.identifier.scopus84904026473
dc.identifier.urihttps://hdl.handle.net/20.500.12645/2689
dc.identifier.wosWOS:000339296900001
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleEfficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameThe Pediatric infectious disease journal
local.avesis.id41c362d3-cc88-41a1-8b7d-894d057658d2
local.avesis.response2559
local.org.facultyTıp Fakültesi
local.publication.goal02 - Açlığa Son
local.publication.isinternational1
relation.isAuthorOfPublication886ea820-98fa-449a-8b4b-26efeff939d8
relation.isAuthorOfPublication29a098c6-acc4-4e05-af39-eeffbc7be778
relation.isAuthorOfPublication.latestForDiscovery886ea820-98fa-449a-8b4b-26efeff939d8
relation.isGoalOfPublication5246edf8-60d4-4a7b-9a27-c73e4a636141
relation.isGoalOfPublication.latestForDiscovery5246edf8-60d4-4a7b-9a27-c73e4a636141
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