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Differential expression of P16 and P21 in benign and malignant uterine smooth muscle tumors

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dc.contributor.authorUnver, NURCAN
dc.contributor.authorAcikalin, Mustafa Fuat
dc.contributor.authorOner, Ulku
dc.contributor.authorCiftci, Evrim
dc.contributor.authorOzalp, S. Sinan
dc.contributor.authorColak, Ertugrul
dc.contributor.institutionauthorÜNVER, NURCAN
dc.date.accessioned2020-10-29T21:34:46Z
dc.date.available2020-10-29T21:34:46Z
dc.date.issued2011-08-01T00:00:00Z
dc.description.abstractThe diagnosis of benign and malignant uterine smooth muscle tumors depends on morphologic criteria such as nuclear atypia, coagulative tumor cell necrosis and mitotic activity. Most of these tumors are readily classifiable into benign or malignant categories using these criteria. However, the distinction between leiomyomas and leiomyosarcomas may at times be problematic. Hence, it would be useful to have additional markers which could help to distinguish these tumors. The aim of the study was to evaluate p16 and p21 expressions in uterine smooth muscle tumors and determine whether p16 and p21 have a potential value in the differential diagnosis of problematic cases. In addition, we evaluated whether the differential expression of p16 and p21 in uterine leiomyosarcomas correlated with tumor recurrence and patient survival.
dc.identifier.citationUnver N., Acikalin M. F. , Oner U., Ciftci E., Ozalp S. S. , Colak E., -Differential expression of P16 and P21 in benign and malignant uterine smooth muscle tumors-, ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.284, ss.483-490, 2011
dc.identifier.doi10.1007/s00404-010-1690-z
dc.identifier.scopus80052311933
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26332
dc.identifier.wosWOS:000292651600034
dc.titleDifferential expression of P16 and P21 in benign and malignant uterine smooth muscle tumors
dc.typeArticle
dspace.entity.typePublication
local.avesis.id91141ebb-0378-4ce2-81c5-2c2c3e1cb3b7
local.publication.isinternational1
relation.isAuthorOfPublication884711f3-71a4-47dd-88e7-486287ed148d
relation.isAuthorOfPublication.latestForDiscovery884711f3-71a4-47dd-88e7-486287ed148d
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