Publication: Chemical constituents of essential oil of endemic Rhanterium suaveolens Desf. growing in Algerian Sahara with antibiofilm, antioxidant and anticholinesterase activities
Program
Authors
Authors
Chemsa, Ahmed Elkhalifa
Erol, EBRU
Ozturk, Mehmet
Zellagui, Amar
Ozgur, Ceylan
Gherraf, Noureddine
Duru, Mehmet Emin
Advisor
Language
Type
Publisher
Journal Title
Journal ISSN
Volume Title
Abstract
Twenty compounds were detected in the essential oil of Rhanterium suaveolens representing 98.01% of the total oil content. Perillaldehyde (45.79%), caryophyllene oxide (24.82%) and -cadinol (5.61%) were identified as the main constituents. In -carotene-linoleic acid assay, both the oil and the methanol extract exhibited good lipid peroxidation inhibition activity, with IC50 values of 17.97 +/- 5.40 and 11.55 +/- 3.39g/mL, respectively. In DPPH and CUPRAC assays, however, the methanol extract exhibited a good antioxidant activity. The highest antibiofilm activity has been found 50.30% against Staphylococcus epidermidis (MU 30) at 20g/mL for essential oil and 58.34% against Micrococcus luteus (NRRL B-4375) at 25mg/mL concentration for methanol extract. The in vitro anticholinesterase activity of methanol extract showed a moderate acetylcholinesterase inhibitory (IC50=168.76 +/- 0.62g/mL) and good butyrylcholinesterase inhibitory (IC50=54.79 +/- 1.89g/mL) activities. The essential oil was inactive against both enzymes.
Description
Source:
Keywords:
Keywords
Citation
Chemsa A. E. , Erol E., Ozturk M., Zellagui A., Ozgur C., Gherraf N., Duru M. E. , -Chemical constituents of essential oil of endemic Rhanterium suaveolens Desf. growing in Algerian Sahara with antibiofilm, antioxidant and anticholinesterase activities-, NATURAL PRODUCT RESEARCH, cilt.30, sa.18, ss.2120-2124, 2016