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Role of gut microbiota: Obesity and NAFLD

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dc.contributor.authorGANGARAPU, Venkatanarayana
dc.contributor.authorYILDIZ, Kemal
dc.contributor.authorInce, ALİ TÜZÜN
dc.contributor.authorBAYSAL, Birol
dc.contributor.institutionauthorİNCE, ALİ TÜZÜN
dc.date.accessioned2019-10-05T12:54:32Z
dc.date.available2019-10-05T12:54:32Z
dc.date.issued2014-04-01
dc.description.abstractNon-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease in developed countries. Obesity is the most important risk factor for metabolic syndrome and NAFLD. Accumulated evidence has revealed that gut microbial compositional changes may be associated with more energy harvesting from the diet, which promotes increased fatty acid uptake from adipose tissue and shifts lipid metabolism from oxidation to de novo production. Furthermore, changes in intestinal barrier function contribute to metabolic endotoxemia in the form of low-grade microbial inflammation. Persistent inflammation exacerbates NAFLD progression. In this review, we discuss the role of gut microbiota in obesity and NAFLD.en
dc.identifier10.3233/ch-2009-1146
dc.identifier.citationGANGARAPU V., YILDIZ K., Ince A. T. , BAYSAL B., -Role of gut microbiota: Obesity and NAFLD-, TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.25, ss.133-140, 2014
dc.identifier.doi10.5152/tjg.2014.7886
dc.identifier.pubmed25003671
dc.identifier.scopus84905489615
dc.identifier.trdizinISSN: 1300-4948 / 2148-5607
dc.identifier.trdizinISSN: 1300-4948 / 2148-5607
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/886
dc.identifier.wosWOS:000339310300003
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectNAFLD
dc.titleRole of gut microbiota: Obesity and NAFLD
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameCLINICAL HEMORHEOLOGY AND MICROCIRCULATION
local.avesis.id1401b60d-15c6-41fa-9b35-928f580b5ad1
local.avesis.response756
local.org.facultyTıp Fakültesi
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication6daa6ab7-ee45-4f50-9e71-e831046b6462
relation.isAuthorOfPublication.latestForDiscovery6daa6ab7-ee45-4f50-9e71-e831046b6462
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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