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Thymoquinone Enhances the Effect of Gamma Knife in B16-F10 Melanoma Through Inhibition of Phosphorylated STAT3

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dc.contributor.authorHATİBOĞLU, MUSTAFA AZİZ
dc.contributor.authorHATİBOĞLU, MUSTAFA AZİZ
dc.contributor.authorKOÇYİĞİT, ABDÜRRAHİM
dc.contributor.authorGÜLER, ERAY METİN
dc.contributor.authorKhan, Imran
dc.contributor.authorKHAN, IMRAN
dc.contributor.authorKarataş, Ersin
dc.contributor.authorTÜZGEN, SAFFET
dc.date.accessioned2019-10-05T21:27:19Z
dc.date.available2019-10-05T21:27:19Z
dc.date.issued2019-01-01
dc.description.abstractBACKGROUND: Patients with brain metastasis from melanoma have a dismal prognosis with poor survival time. Gamma Knife (GK) is an effective treatment to control brain metastasis from melanoma. Thymoquinone (TQ) has emerged as a potential therapeutic option due to its antiproliferative effects on various cancers. The purpose of the study was to assess the effect of GK on B16-F10 melanoma cells in vitro and intracerebral melanoma in vivo, and its synergistic effect in combination with TQ.
dc.description.sponsorshipBezmiâlem Vakıf Üniversitesi
dc.identifier10.1258/0022215011908432
dc.identifier.citationHATİBOĞLU M. A. , KOÇYİĞİT A., GÜLER E. M. , Akdur K., Khan I., Nalli A., Karataş E., TÜZGEN S., -Thymoquinone Enhances the Effect of Gamma Knife in B16-F10 Melanoma Through Inhibition of Phosphorylated STAT3-, WORLD NEUROSURGERY, cilt.128, ss.570-581, 2019
dc.identifier.doi10.1016/j.wneu.2019.04.205
dc.identifier.pubmed31054338
dc.identifier.scopus85066603526
dc.identifier.urihttps://hdl.handle.net/20.500.12645/7339
dc.identifier.wosWOS:000475895100067
dc.language.isoen
dc.titleThymoquinone Enhances the Effect of Gamma Knife in B16-F10 Melanoma Through Inhibition of Phosphorylated STAT3
dc.typeArticle
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local.article.journalnameJOURNAL OF LARYNGOLOGY AND OTOLOGY
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