Publication: Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia
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Authors
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TAKIR, Mumtaz
KOSTEK, Osman
OZKOK, Abdullah
Elcioglu, Omer Celal
BAKAN, Ali
EREK, Aybala
MUTLU, Hasan Huseyin
TELCI, Ozge
SEMERCI, Aysun
ODABAS, Ali Riza
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Abstract
Background Hyperuricemia is an independent predictor of impaired fasting glucose and type 2 diabetes, but whether it has a causal role in insulin resistance remains controversial. Here we tested the hypothesis that lowering uric acid in hyperuricemic nondiabetic subjects might improve insulin resistance.
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Citation
TAKIR M., KOSTEK O., OZKOK A., Elcioglu O. C. , BAKAN A., EREK A., MUTLU H. H. , TELCI O., SEMERCI A., ODABAS A. R. , et al., -Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia-, JOURNAL OF INVESTIGATIVE MEDICINE, cilt.63, ss.924-929, 2015