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Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia

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KOSTEK, Osman

OZKOK, Abdullah

Elcioglu, Omer Celal

BAKAN, Ali

EREK, Aybala

MUTLU, Hasan Huseyin

TELCI, Ozge

SEMERCI, Aysun

ODABAS, Ali Riza

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Background Hyperuricemia is an independent predictor of impaired fasting glucose and type 2 diabetes, but whether it has a causal role in insulin resistance remains controversial. Here we tested the hypothesis that lowering uric acid in hyperuricemic nondiabetic subjects might improve insulin resistance.

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TAKIR M., KOSTEK O., OZKOK A., Elcioglu O. C. , BAKAN A., EREK A., MUTLU H. H. , TELCI O., SEMERCI A., ODABAS A. R. , et al., -Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia-, JOURNAL OF INVESTIGATIVE MEDICINE, cilt.63, ss.924-929, 2015

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