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Bemarituzumab in patients with FGFR2b-selected gastric or gastro-oesophageal junction adenocarcinoma (FIGHT): a randomised, double-blind, placebo-controlled, phase 2 study.

dc.contributor.authorWainberg, Zev A
dc.contributor.authorEnzinger, Peter C
dc.contributor.authorKang, Yoon-Koo
dc.contributor.authorQin, Shukui
dc.contributor.authorYamaguchi, Kensei
dc.contributor.authorKim, In-Ho
dc.contributor.authorSaeed, Anwaar
dc.contributor.authorOh, Sang Cheul
dc.contributor.authorLi, Jin
dc.contributor.authorTurk, HACI MEHMET
dc.contributor.authorTeixeira, Alexandra
dc.contributor.authorBorg, Christophe
dc.contributor.authorHitre, Erika
dc.contributor.authorUdrea, Adrian A
dc.contributor.authorCardellino, Giovanni Gerardo
dc.contributor.authorSanchez, Raquel Guardeño
dc.contributor.authorCollins, Helen
dc.contributor.authorMitra, Siddhartha
dc.contributor.authorYang, Yingsi
dc.contributor.authorCatenacci, Daniel V T
dc.contributor.authorLee, Keun-Wook
dc.contributor.institutionauthorTÜRK, HACI MEHMET
dc.date.accessioned2022-10-18T20:59:14Z
dc.date.available2022-10-18T20:59:14Z
dc.date.issued2022-10-13T00:00:00Z
dc.description.abstractMagnetic monopoles are known to emerge as leading non-perturbative fluctuations in the lattice version of non-Abelian gauge theories in some gauges. In terms of the Dirac quantization condition, these monopoles have magnetic charge |Q_M|=2. Also, magnetic monopoles with |Q_M|=1 can be introduced on the lattice via the -t Hooft loop operator. We consider the |Q_M|=1,2 monopoles in the continuum limit of the lattice gauge theories. To substitute for the Dirac strings which cost no action on the lattice, we allow for singular gauge potentials which are absent in the standard continuum version. Once the Dirac strings are allowed, it turns possible to find a solution with zero action for a monopole--antimonopole pair. This implies equivalence of the standard and modified continuum versions in perturbation theory. To imitate the nonperturbative vacuum, we introduce then a nonsingular background. The modified continuum version of the gluodynamics allows in this case for monopoles with finite non-vanishing action. Using similar techniques, we construct the -t Hooft loop operator in the continuum and predict its behavior at small and large distances both at zero and high temperatures.
dc.identifier.citationWainberg Z. A. , Enzinger P. C. , Kang Y., Qin S., Yamaguchi K., Kim I., Saeed A., Oh S. C. , Li J., Turk H. M. , et al., -Bemarituzumab in patients with FGFR2b-selected gastric or gastro-oesophageal junction adenocarcinoma (FIGHT): a randomised, double-blind, placebo-controlled, phase 2 study.-, The Lancet. Oncology, 2022
dc.identifier.doi10.1016/s1470-2045(22)00603-9
dc.identifier.pubmed36244398
dc.identifier.urihttp://hdl.handle.net/20.500.12645/31143
dc.titleBemarituzumab in patients with FGFR2b-selected gastric or gastro-oesophageal junction adenocarcinoma (FIGHT): a randomised, double-blind, placebo-controlled, phase 2 study.
dc.typeArticle
dspace.entity.typePublication
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local.publication.isinternational1
relation.isAuthorOfPublication1b3a1540-7e57-405d-8a9d-f926d17dcc29
relation.isAuthorOfPublication.latestForDiscovery1b3a1540-7e57-405d-8a9d-f926d17dcc29
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