Publication:
DESIGN AND EVALUATION OF PROPOLIS-HPC/PVP ELECTROSPUN NANOFIBERS FOR POSSIBLE CUTANEOUS APPLICATIONS

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dc.contributor.authorEsentürk-Güzel I.
dc.contributor.authorALĞIN YAPAR E.
dc.contributor.authorCavalu S.
dc.contributor.authorŞEKER İ. T.
dc.contributor.authorİNAL E.
dc.contributor.authorKARTAL M.
dc.contributor.authorKoç R. Ç.
dc.contributor.authorÖztürk R. Y.
dc.contributor.authorGöksu F.
dc.contributor.authorBölek S.
dc.contributor.authoret al.
dc.contributor.institutionauthorİNAL, EBRAR
dc.contributor.institutionauthorKARTAL, MURAT
dc.date.accessioned2024-03-27T21:50:46Z
dc.date.available2024-03-27T21:50:46Z
dc.date.issued2024-01-01
dc.description.abstractThe aim of the study was to prepare propolis loaded hydroxypropyl cellulose and polyvinyl pyrrolidone (HPC/PVP) nanofibers, suitable for cutaneous applications. LC-HRMS analyses were applied for the identification and quantification of the bio-compounds in the propolis extract. Electrospinning was applied in order to prepare propolis HPC/PVP nanofibers with increasing concentration of propolis 10%, 20% and 30 % (v/v) and subsequently characterized in terms of morphology, wettability, thermal degradation and biological properties. SEM images showed homogenous features of the nanofibers and average diameter between 197.2-268.4 nm, high antioxidant activity, very good biocompatibility and no cytotoxicity. Particularly, with the highest propolis concentration, 30-PE/HPC/PVP nanofiber formulation is a promising alternative to conventional treatments for cutaneous applications.
dc.identifier.citationEsentürk-Güzel I., ALĞIN YAPAR E., Cavalu S., ŞEKER İ. T., İNAL E., KARTAL M., Koç R. Ç., Öztürk R. Y., Göksu F., Bölek S., et al., "DESIGN AND EVALUATION OF PROPOLIS-HPC/PVP ELECTROSPUN NANOFIBERS FOR POSSIBLE CUTANEOUS APPLICATIONS", Farmacia, cilt.72, sa.1, ss.200-213, 2024
dc.identifier.doi10.31925/farmacia.2024.1.22
dc.identifier.endpage213
dc.identifier.issn0014-8237
dc.identifier.issue1
dc.identifier.scopus85186181572
dc.identifier.startpage200
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85186181572&origin=inward
dc.identifier.urihttps://hdl.handle.net/20.500.12645/39175
dc.identifier.volume72
dc.relation.ispartofFarmacia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectPharmacology and Therapeutics
dc.subjectBasic Pharmaceutics Sciences
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectLife Sciences (LIFE)
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectPHARMACOLOGY & PHARMACY
dc.subjectGenel Farmakoloji, Toksikoloji ve Eczacılık
dc.subjectGeneral Pharmacology, Toxicology and Pharmaceutics
dc.subjectbiocompatibility
dc.subjectelectrospinning
dc.subjecthdroxypropylcellulose
dc.subjectnanofibers
dc.subjectpolyvinyl pyrollidone
dc.subjectpropolis
dc.titleDESIGN AND EVALUATION OF PROPOLIS-HPC/PVP ELECTROSPUN NANOFIBERS FOR POSSIBLE CUTANEOUS APPLICATIONS
dc.typearticle
dspace.entity.typePublication
local.avesis.id403d22a9-aad9-4ab8-aa5b-4c48044c2a17
relation.isAuthorOfPublicationed5665e2-6fa1-4058-8198-9f5ab47a40d0
relation.isAuthorOfPublicationb30ec030-5f34-4c8b-814e-a7131d524a0a
relation.isAuthorOfPublication.latestForDiscoveryed5665e2-6fa1-4058-8198-9f5ab47a40d0
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