Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease

Abstract

Background and ObjectivePeriostin, a secreted adhesion molecule essential for periodontal tissue integrity, is highly expressed in the periodontal ligament and plays a critical role in tooth and bone development. The purpose of this study was to investigate periostin levels in the gingival crevicular fluid and serum of patients with periodontal disease and compare them with those of healthy individuals.