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Now showing 1 - 10 of 33
  • PublicationMetadata only
    Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease
    (2015-12-01T00:00:00Z) Balli, UMUT; Keles, Z. P.; Avci, B.; Guler, S.; Cetinkaya, B. O.; Keles, G. C.; BALLI, UMUT
    Background and ObjectivePeriostin, a secreted adhesion molecule essential for periodontal tissue integrity, is highly expressed in the periodontal ligament and plays a critical role in tooth and bone development. The purpose of this study was to investigate periostin levels in the gingival crevicular fluid and serum of patients with periodontal disease and compare them with those of healthy individuals.
  • PublicationMetadata only
    Concentrated growth factor in the treatment of adjacent multiple gingival recessions: a split-mouth randomized clinical trial
    (2015-09-01T00:00:00Z) Dogan, Seyma Bozkurt; Dede, Figen Ongoz; Balli, UMUT; Atalay, Elif N.; Durmuslar, Mustafa C.; BALLI, UMUT
    AimThe aim of this study was to determine the clinical effect of concentrated growth factor (CGF) in combination with coronally advanced flap (CAF) compared to CAF alone for the treatment of multiple adjacent gingival recessions (GRs).
  • PublicationMetadata only
    Assessment of Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 in the Periodontium of Rats Treated With Atorvastatin
    (2014-01-01T00:00:00Z) Balli, UMUT; Keles, Gonca Cayir; Cetinkaya, Burcu Ozkan; Mercan, Ugur; Ayas, Bulent; Erdogan, Deniz; BALLI, UMUT
    Background: The aim of this study is to examine, for the first time, the role of systemic and local atorvastatin application on periodontium using histomorphometric and immunohistochemical analysis during and after experimental periodontitis induction with or without the presence of microbial dental biofilm.
  • PublicationMetadata only
    The effect of initial periodontal treatment on plasma, gingival crevicular fluid and salivary levels of 8-hydroxy-deoxyguanosine in obesity
    (2016-02-01T00:00:00Z) Dede, Figen Ongoz; Dogan, Seyma Bozkurt; Balli, UMUT; Avci, Bahattin; Durmuslar, Mustafa Cenk; BALLI, UMUT
    Objective: Recent studies have shown adverse effects on the periodontium from the increased production of reactive oxygen species (ROS) in obesity. The purpose of this study was to investigate the effects of obesity on 8-hydroxy-deoxyguanosine (8-OHdG) levels in the bodily fluids of patients with and without periodontal disease and to evaluate changes after initial periodontal treatment.
  • PublicationMetadata only
    The levels of visceral adipose tissue-derived serpin, omentin-1 and tumor necrosis factor-alpha in the gingival crevicular fluid of obese patients following periodontal therapy
    (2016-12-01T00:00:00Z) Balli, UMUT; Dogan, Seyma Bozkurt; Dede, Figen Ongoz; Sertoglu, Erdim; Keles, Gonca Cayir; BALLI, UMUT
    The aim of this clinical study was to determine levels of visceral adipose tissue-derived serpin (vaspin), omentin-1, and tumor necrosis factor-alpha (TNF-alpha) in the gingival crevicular fluid (GCF) of obese and non-obese periodontitis patients following nonsurgical periodontal therapy. Seventy-six subjects were separated into four groups according to periodontal and anthropometric measurements: a periodontal-healthy group, a chronic periodontitis (CP) group, a periodontal-healthy with obesity group, and a CP with obesity group. Nonsurgical periodontal treatment was administered to periodontitis patients. Before treatment and at 6 weeks after treatment, GCF samples were analyzed and clinical periodontal parameters were examined. Enzyme-linked immunosorbent assays were used to measure the levels of vaspin, omentin-1, and TNF-a. Obese and non-obese CP patients displayed higher levels of vaspin and TNF-alpha (P < 0.008), which declined following treatment (P< 0.025), and lower omentin levels (P <0.008), which increased after treatment (P < 0.025). There was a negative correlation between the total amount of vaspin and omentin-1 in all groups. Obese and non-obese patients had opposing levels of vaspin and omentin-1 in the GCF; therefore, these may represent diagnostic and prognostic indicators of periodontal disease and therapeutic outcome.
  • PublicationMetadata only
    Chemerin as a Novel Crevicular Fluid Marker of Patients With Periodontitis and Type 2 Diabetes Mellitus
    (2016-08-01T00:00:00Z) Dogan, Seyma Bozkurt; Balli, UMUT; Dede, Figen Ongoz; Sertoglu, Erdim; Tazegul, Kaan; BALLI, UMUT
    Background: The objectives of the present study are to: 1) determine whether gingival crevicular fluid (GCF) chemerin is a novel predictive marker for patients with chronic periodontitis (CP) with and without type 2 diabetes mellitus (t2DM); 2) analyze the relationship between chemerin and interleukin (IL)-6 in periodontally healthy individuals and in patients with CP and with and without t2DM; and 3) evaluate the effect of non-surgical periodontal therapy on GCF chemerin levels.
  • PublicationMetadata only
    Impact of Three Different Education Methods on Oral Hygiene and Theoretical Knowledge of Schoolchildren
    (2018-01-01T00:00:00Z) Demiriz, Levent; Dede, Figen Ongoz; Balli, UMUT; BALLI, UMUT
    Objective: To evaluate the impact of three different education methods on the oral hygiene levels of school children using clinical and theoretical findings. Material and Methods: 144 children (72 males and 72 females), whose ages ranged between 8-13, were divided into 12 equal experimental groups according to their ages and gender. They were all considered to have poor hygiene. Only one out of the three different education methods (brochure, model or video) was applied to each group. The percentage change in PI, GI, BOP and theoretical test points from the baseline to the 6th months were evaluated. The data was statistically analysed by using Kolmogorov-Smirnov and One-way ANOVA tests. Results: Reduction in PI, GI and BOP scores was significantly greater (p0.05). There was no significant difference in test points in 8-10 and 11-13-year-old female groups (p>0.05), whereas a significant increase in test points was observed in the video and model applied groups compared to the brochure groups in 8-10 and 11-13-year-old male groups (p<0.05). Conclusion: It may be more helpful and effective for children to get the oral hygiene education using the visual methods, especially for those under the age of ten.
  • PublicationMetadata only
    Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol
    (2016-04-01T00:00:00Z) Balli, UMUT; Cetinkaya, Burcu Ozkan; Keles, Gonca Cayir; Keles, Zeynep Pinar; Guler, Sevki; Sogut, Mehtap Unlu; Erisgin, Zuleyha; BALLI, UMUT
    Purpose: The objective of this study was to investigate the effect of a dietary flavonoid, kaempferol, which has been shown to possess antiallergic, anti-inflammatory, anticarcinogenic, and antioxidant activities on the periodontium by histomorphometric analysis and on gingival tissue matrix metalloproteinase-1 (MMP-1), MMP-8, and tissue inhibitor of metalloproteinase-2 (TIMP-2) by biochemical analysis of rats after experimental periodontitis induction.
  • PublicationMetadata only
    The effect of infliximab on bone healing in osteoporotic rats
    (2016-04-01T00:00:00Z) Durmuslar, M. Cenk; Turer, Akif; Balli, UMUT; Yilmaz, Zehra; Onger, Mehmet Emin; Celik, H. Hamdi; Vatansever, Alper; BALLI, UMUT
    Purpose: The aim of this study was to evaluate the effect of the infliximab on autogenous-mediated bone regeneration and resorption of autogenous graft in the ovariectomised rat model.
  • PublicationMetadata only
    The influence of oral administration of rosuvastatin on calvarial bone healing in rats
    (2016-09-01T00:00:00Z) Turer, Akif; Turer, Cigdem Coskun; Durmuslar, M. Cenk; Balli, UMUT; Onger, M. Emin; BALLI, UMUT
    The purpose of this study is to investigate the potential of the systemic administration of different doses of rosuvastatin (RSV) on autogenous grafted critical-sized cortical bone defects. Twenty-four rats were divided into three groups: Group C (control), Group RSV-2 and Group RSV-5. A 5-mm diameter critical size defect was created in the calvarium of each animal. In Group C, the defect was filled by autogenous graft only and rats were given saline solution with oral gavage for 28 days. In Group RSV-2 defects were filled with autogenous graft and rats were given 2 mg/kg rosuvastatin with oral gavage for 28 days. In Group RSV-5 defects were filled with autogenous graft and rats were given 5 mg/kg rosuvastatin with oral gavage for 28 days. All animals were euthanized at 28 days postoperative. Stereologic and micro-CT analyses were performed. New bone area (NBA) and connective tissue volumes were measured. Stereologic analysis showed that Group RSV-5 and RSV-2 had significantly more new bone at 4 weeks compared with group C. Connective tissue volumes were also significantly higher in RSV applicated groups. New bone and connective tissue volumes- difference were not statistically significant between RSV groups. Micro-CT results were similar with stereologic analyses. Orally administered RSV enhances bone regeneration in critical size calvarial rat defects filled with autogenous graft furthermore possible inflammatory effect should be investigated. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.