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International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

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Kilic, Atila
Rosenthal, Victor Daniel
Maki, Dennis George
Mehta, Yatin
Leblebicioglu, Hakan
Memish, Ziad Ahmed
Al-Mousa, Haifaa Hassan
Balkhy, Hanan
Hu, Bijie
Alvarez-Moreno, Carlos

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We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention-s (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC-s ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC-s ICUs was similar to that reported from ICUs in the U.S. in the CDC-s NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line-associated bloodstream infection in the INICC-s ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U. S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC-s ICUs compared with the ICUs of the CDC-s NHSN. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

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Rosenthal V. D. , Maki D. G. , Mehta Y., Leblebicioglu H., Memish Z. A. , Al-Mousa H. H. , Balkhy H., Hu B., Alvarez-Moreno C., Medeiros E. A. , et al., -International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module-, AMERICAN JOURNAL OF INFECTION CONTROL, cilt.42, ss.942-956, 2014

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