Publication:
SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion

dc.contributor.authorDe Luca, Giuseppe
dc.contributor.authorAlgowhary, Magdy
dc.contributor.authorUguz, Berat
dc.contributor.authorOliveira, Dinaldo C.
dc.contributor.authorGanyukov, Vladimir
dc.contributor.authorZimbakov, Zan
dc.contributor.authorCercek, Miha
dc.contributor.authorJensen, Lisette Okkels
dc.contributor.authorLoh, Poay Huan
dc.contributor.authorCalmac, Lucian
dc.contributor.authorFerrer, Gerard Roura
dc.contributor.authorQuadros, Alexandre
dc.contributor.authorMilewski, Marek
dc.contributor.authorDi Uccio, Fortunato Scotto
dc.contributor.authorvon Birgelen, Clemens
dc.contributor.authorVersaci, Francesco
dc.contributor.authorTen Berg, Jurrien
dc.contributor.authorCasella, Gianni
dc.contributor.authorLung, Aaron Wong Sung
dc.contributor.authorKala, Petr
dc.contributor.authorGil, Jose Luis Diez
dc.contributor.authorCarrillo, Xavier
dc.contributor.authorDirksen, Maurits
dc.contributor.authorBecerra-Munoz, Victor M.
dc.contributor.authorLee, Michael Kang-Yin
dc.contributor.authorJuzar, Dafsah Arifa
dc.contributor.authorJoaquim, Rodrigo de Moura
dc.contributor.authorDe Simone, Ciro
dc.contributor.authorMilicic, Davor
dc.contributor.authorDavlouros, Periklis
dc.contributor.authorBakraceski, Nikola
dc.contributor.authorZilio, Filippo
dc.contributor.authorDonazzan, Luca
dc.contributor.authorKraaijeveld, Adriaan
dc.contributor.authorGalasso, Gennaro
dc.contributor.authorArpad, Lux
dc.contributor.authorMarinucci, Lucia
dc.contributor.authorGuiducci, Vincenzo
dc.contributor.authorMenichelli, Maurizio
dc.contributor.authorScoccia, Alessandra
dc.contributor.authorYamac, Aylin Hatice
dc.contributor.authorMERT, KADİR UĞUR
dc.contributor.authorRios, Xacobe Flores
dc.contributor.authorKovarnik, Tomas
dc.contributor.authorKidawa, Michal
dc.contributor.authorMoreu, Jose
dc.contributor.authorFlavien, Vincent
dc.contributor.authorFabris, Enrico
dc.contributor.authorMartinez-Luengas, Inigo Lozano
dc.contributor.authorBoccalatte, Marco
dc.contributor.authorOjeda, Francisco Bosa
dc.contributor.authorArellano-Serrano, Carlos
dc.contributor.authorCaiazzo, Gianluca
dc.contributor.authorCirrincione, Giuseppe
dc.contributor.authorKao, Hsien-Li
dc.contributor.authorFores, Juan Sanchis
dc.contributor.authorVignali, Luigi
dc.contributor.authorPereira, Helder
dc.contributor.authorManzo-Silbermann, Stephane
dc.contributor.authorOrdonez, Santiago
dc.contributor.authorOzkan, Alev Arat
dc.contributor.authorScheller, Bruno
dc.contributor.authorLehtola, Heidi
dc.contributor.authorTeles, Rui
dc.contributor.authorMantis, Christos
dc.contributor.authorAntti, Ylitalo
dc.contributor.authorSilveira, Joao Antonio Brum
dc.contributor.authorBessonov, Ivan
dc.contributor.authorZoni, Rodrigo
dc.contributor.authorSavonitto, Stefano
dc.contributor.authorKochiadakis, George
dc.contributor.authorAlexopoulos, Dimitrios
dc.contributor.authorUribe, Carlos E.
dc.contributor.authorKanakakis, John
dc.contributor.authorFaurie, Benjamin
dc.contributor.authorGabrielli, Gabriele
dc.contributor.authorBarrios, Alejandro Gutierrez
dc.contributor.authorBachini, Juan Pablo
dc.contributor.authorRocha, Alex
dc.contributor.authorTam, Frankie Chor-Cheung
dc.contributor.authorRodriguez, Alfredo
dc.contributor.authorLukito, Antonia Anna
dc.contributor.authorBellemain-Appaix, Anne
dc.contributor.authorPessah, Gustavo
dc.contributor.authorCortese, Giuliana
dc.contributor.authorParodi, Guido
dc.contributor.authorBurgadha, Mohammed Abed
dc.contributor.authorKedhi, Elvin
dc.contributor.authorLamelas, Pablo
dc.contributor.authorSuryapranata, Harry
dc.contributor.authorNardin, Matteo
dc.contributor.authorVerdoia, Monica
dc.contributor.institutionauthorYAMAÇ, AYLİN HATİCE
dc.date.accessioned2022-10-25T20:59:09Z
dc.date.available2022-10-25T20:59:09Z
dc.date.issued2022-10-01T00:00:00Z
dc.description.abstractSARS-Cov-2 has been suggested to promote thrombotic complications and higher mortality. The aim of the present study was to evaluate the impact of SARS-CoV-2 positivity on in-hospital outcome and 30-day mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) enrolled in the International Survey on Acute Coronary Syndromes ST-segment elevation Myocardial Infarction (ISACS-STEMI COVID-19 registry. The 109 SARS-CoV-2 positive patients were compared with 2005 SARS-CoV-2 negative patients. Positive patients were older (P = .002), less often active smokers (P = .002), and hypercholesterolemic (P = .006), they presented more often later than 12 h (P = .037), more often to the hub and were more often in cardiogenic shock (P = .02), or requiring rescue percutaneous coronary intervention after failed thrombolysis (P < .0001). Lower postprocedural Thrombolysis in Myocardial Infarction 3 flow (P = .029) and more thrombectomy (P = .046) were observed. SARS-CoV-2 was associated with a significantly higher in-hospital mortality (25.7 vs 7%, adjusted Odds Ratio (OR) [95% Confidence Interval] = 3.2 [1.71-5.99], P < .001) in-hospital definite in-stent thrombosis (6.4 vs 1.1%, adjusted Odds Ratio [95% CI] = 6.26 [2.41-16.25], P < .001) and 30-day mortality (34.4 vs 8.5%, adjusted Hazard Ratio [95% CI] = 2.16 [1.45-3.23], P < .001), confirming that SARS-CoV-2 positivity is associated with impaired reperfusion, with negative prognostic consequences.
dc.identifier.citationDe Luca G., Algowhary M., Uguz B., Oliveira D. C. , Ganyukov V., Zimbakov Z., Cercek M., Jensen L. O. , Loh P. H. , Calmac L., et al., -SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion-, ANGIOLOGY, 2022
dc.identifier.doi10.1177/00033197221129351
dc.identifier.pubmed36222189
dc.identifier.urihttp://hdl.handle.net/20.500.12645/31167
dc.identifier.wosWOS:000866193900001
dc.titleSARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion
dc.typeArticle
dspace.entity.typePublication
local.avesis.id1f79874e-69ed-4580-8075-5c7c7655a3fe
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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relation.isAuthorOfPublication.latestForDiscovery9170fc79-989a-4ba8-b610-a6b256302c5a
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relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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