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Co-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report

dc.contributor.authorUnver, NURCAN
dc.contributor.authorCoban, GANİME
dc.contributor.authorONARAN, Oyku Izel
dc.contributor.authorARSLAN, ADNAN
dc.contributor.authorMalya, FATMA ÜMİT
dc.contributor.authorHASBAHCECI, Mustafa
dc.contributor.institutionauthorÜNVER, NURCAN
dc.contributor.institutionauthorÇOBAN, GANİME
dc.contributor.institutionauthorKUNDUZ, ENVER
dc.contributor.institutionauthorARSLAN, ADNAN
dc.contributor.institutionauthorMALYA, FATMA ÜMİT
dc.date.accessioned2019-10-05T21:14:48Z
dc.date.available2019-10-05T21:14:48Z
dc.date.issued2015-09-01
dc.description.abstractIntroduction: Inflammatory myofibroblastic tumor as a rare neoplastic lesion is seen most commonly in the pulmonary system. Beside the presence of limited number of inflammatory myofibroblastic tumors of the gastrointestinal tract in the literature, co-existence with acute appendicitis has not been reported before. Presentation of case: A 27-year-old woman admitted to emergency department with acute abdominal pain at the right lower quadrant. The initial diagnosis was as acute appendicitis. Intraoperatively, a mass with a diameter of almost 5 cm originated from the distal ileal segments neighboring the appendix was seen. The patient was managed by segmental resection of the small intestine including the mass with appendectomy. Histologically, there were bundles of spindle cells accompanied by lymphoplasmocytic infiltration. The immunohistochemical studies showed that tumor cells were positive for smooth muscle actin, vimentin, perinuclear activity for anaplastic lymphoma kinase and CD 68. The final pathologic diagnosis was inflammatory myofibroblastic tumor. Discussion: Concomitant resection of tumoral lesions detected in the neighbor intestinal segments during appendectomy should be considered to diagnose and treat. For the diagnosis of inflammatory myofibroblastic tumor, immunohistochemistry pattern including positivity for actin, vimentin, CD 68 and anaplastic lymphoma kinase plays a crucial role. Therefore, detailed immunohistochemistry analysis should be performed in suspicious cases. Conclusion: Coexistence of inflammatory myofibroblastic tumor located in the gastrointestinal system with acute appendicitis is a rare event. Complete surgical excision should be regarded as the mainstay of the treatment. Long-term follow up with serial imaging techniques is recommended.en
dc.identifier10.1590/1678.775720160010
dc.identifier.citationUnver N., Coban G., ONARAN O. I. , Kunduz E., ARSLAN A., Malya F. Ü. , HASBAHCECI M., -Co-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report-, ANNALS OF MEDICINE AND SURGERY, cilt.4, ss.217-220, 2015
dc.identifier.pubmed26236476
dc.identifier.urihttps://hdl.handle.net/20.500.12645/6863
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjecttumor
dc.titleCo-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF APPLIED ORAL SCIENCE
local.avesis.idaba17a8e-b493-4e39-a16c-5b20b7e52092
local.avesis.response6739
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relation.isAuthorOfPublication.latestForDiscoverydac57ed0-e32e-4123-9b10-3028d63daf1f
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