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Analysis of infectious spondylodiscitis: 7-years data

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dc.contributor.authorKoc, Meliha Meric
dc.contributor.authorOkay, GÜLAY
dc.contributor.authorAkkoyunlu, YASEMİN
dc.contributor.authorBolukcu, SİBEL
dc.contributor.authorDurdu, BÜLENT
dc.contributor.authorHakyemez, Ismail Necati
dc.contributor.institutionauthorOKAY, GÜLAY
dc.contributor.institutionauthorAKKOYUNLU, YASEMİN
dc.contributor.institutionauthorBOLUKÇU, SİBEL
dc.contributor.institutionauthorDURDU, BÜLENT
dc.contributor.institutionauthorHAKYEMEZ, İSMAİL NECATİ
dc.contributor.institutionauthorMERİÇ KOÇ, MELİHA
dc.date.accessioned2019-10-05T14:52:23Z
dc.date.available2019-10-05T14:52:23Z
dc.date.issued2018-11-01
dc.description.abstractObjective: Infectious spondylodiscitis (SD) is an infectious disease that is rare and difficult to diagnose due to its non-specific clinical features. In this study, we aimed to describe the clinical and diagnostic features of infectious spondylodiscitis. Methods: All patients who were diagnosed with SD at our hospital during a 7-year period from January 1, 2011 through December 31, 2017 were included in the study. Spondylodiscitis is divided into the following three types: pyogenic, tuberculous, and brucellar. Clinical and laboratory data were collected retrospectively from the medical records of the patients. Results: Of the 118 patients, 66 (55.9%) were female, 81 (68.6%) had pyogenic SD (PSD), 21 (17.8%) had tuberculous SD (TSD), and 16 (13.6%) had brucellar SD (BSD). The mean age was 59.3 ± 14.6 years. Leucocytosis was significantly higher in patients with PSD (p=0.01) than in patients with other types of SD. Thoracic involvement (47.6%) was significantly higher in patients with TSD (p=0.005) than in other patients. Sacral involvement (12.5%) was significantly higher in patients with BSD (p=0.01) than in other patients. Paravertebral abscess formation (42.8%) occurred most frequently in patients with TSD. Microbiologic agents were defined in 50% (18/36) of the surgical specimens and in 12.5% of the fine needle aspiration biopsy (FNAB) specimens. Staphylococcus aureus was the most common microbiological agent in patients with PSD. Spinal surgery was defined as a risk factor for PSD (p = 0.0001). Binary logistic regression analysis revealed that female gender, thoracic involvement and night sweats were the predictive markers for TSD (OR 4.5 [95% CI 1.3-15.3] and OR 5 [95% CI 1.7-14.6]). Conclusion: PSD is the most frequent form of SD. Leucocytosis is most common in patients with PSD. Thoracic involvement and paraspinal abscess were prominent in patients with TSD. Sacral involvement was most common in patients with BSD. Thoracic involvement, female gender and night sweats were the predictive markers for TSD. The microbiological culture positivity rate was higher in surgical specimens compared to FNAB specimens. The need for surgical treatment was most common in patients with TSD.en
dc.identifier10.3906/kim-1403-47
dc.identifier.citationOkay G., Akkoyunlu Y., Bolukcu S., Durdu B., Hakyemez I. N. , Koc M. M. , -Analysis of infectious spondylodiscitis: 7-years data-, PAKISTAN JOURNAL OF MEDICAL SCIENCES, cilt.34, ss.1445-1451, 2018
dc.identifier.pubmed30559801
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4925
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleAnalysis of infectious spondylodiscitis: 7-years data
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameTURKISH JOURNAL OF CHEMISTRY
local.avesis.id792065fc-060a-411a-95ac-1fd2e2acc792
local.avesis.response4795
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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