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Assessment of the Relationship between Monocyte to High-Density Lipoprotein Ratio and Myocardial Bridge.

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dc.contributor.authorBakshaliyev, N
dc.contributor.authorKaracop, E
dc.contributor.authorCosansu, K
dc.contributor.authorHuyut, MA
dc.contributor.authorTurna, F
dc.contributor.authorEnhos, A
dc.contributor.authorNadir, A
dc.contributor.authorOzdemir, R
dc.contributor.authorUluganyan, MAHMUT
dc.contributor.institutionauthorENHOŞ, ASIM
dc.contributor.institutionauthorKARAÇÖP, ERDEM
dc.contributor.institutionauthorBAKHSALIYEV, NIJAD
dc.contributor.institutionauthorNADİR, AYDIN
dc.contributor.institutionauthorÖZDEMİR, RAMAZAN
dc.contributor.institutionauthorULUGANYAN, MAHMUT
dc.date.accessioned2020-10-29T14:43:55Z
dc.date.available2020-10-29T14:43:55Z
dc.date.issued2019-01-01T00:00:00Z
dc.description.abstractBackground: Assessing the monocyte to high-density lipoprotein ratio (MHR) is a new tool for predicting inflamation, which plays a major role in atherosclerosis. Myocardial bridge (MB) is thought to be a benign condition with development of atherosclerosis, particularly at the proximal segment of the brigde. Objective: To evaluate the relationhip between MHR and the presence of MB. Methods: We consecutively scanned patients referred for coronary angiography between January 2013- December 2016, and a total of 160 patients who had a MB and normal coronary artery were enrolled in the study. The patients’ angiographic, demographic and clinic characteristics of the patients were reviewed from medical records. Monocytes and HDL-cholesterols were measured via complete blood count. MHR was calculated as the ratio of the absolute monocyte count to the HDL-cholesterol value. MHR values were divided into three tertiles as follows: lower (8.25 ± 1.61), moderate (13.11 ± 1.46), and higher (21.21 ± 4.30) tertile. A p-value of < 0.05 was considered significant. Results: MHR was significantly higher in the MB group compared to the control group with normal coronary arteries. We found the frequency of MB (p = 0.002) to increase as the MHR tertiles rose. The Monocyte-HDL ratio with a cut-point of 13.35 had 59% sensitivity and 65.0% specificity (ROC area under curve: 0.687, 95% CI: 0.606-0.769, p < 0.001) in accurately predicting a MB diagnosis. In the multivariate analysis, MHR (p = 0.013) was found to be a significant independent predictor of the presence of MB, after adjusting for other risk factors. Conclusion: The present study revealed a significant correlation between MHR and MB.
dc.identifier.citationEnhos A., Cosansu K., Huyut M., Turna F., Karacop E., Bakshaliyev N., Nadir A., Ozdemir R., Uluganyan M., -Assessment of the Relationship between Monocyte to High-Density Lipoprotein Ratio and Myocardial Bridge.-, Arquivos brasileiros de cardiologia, cilt.112, ss.12-17, 2019
dc.identifier.doi10.5935/abc.20180253
dc.identifier.pubmed30570069
dc.identifier.scopus85060395927
dc.identifier.trdizintrdizin
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25410
dc.identifier.urihttps://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005020106&lng=en&nrm=iso&tlng=en
dc.identifier.wosWOS:000456285100004
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiomarkers/blood
dc.titleAssessment of the Relationship between Monocyte to High-Density Lipoprotein Ratio and Myocardial Bridge.
dc.typeArticle
dspace.entity.typePublication
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