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Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis

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dc.contributor.authorOzturk, Erdogan
dc.contributor.authorSurucu, Murat
dc.contributor.authorKaraman, Abdurrahman
dc.contributor.authorŞAMDANCI, EMİNE
dc.contributor.authorFadillioglu, Ersin
dc.date.accessioned2020-10-22T18:37:05Z
dc.date.available2020-10-22T18:37:05Z
dc.date.issued2014-04-01T00:00:00Z
dc.description.abstractBackground: Sepsis is defined as an uncontrolled inflammatory response in a host. The process may lead to severe sepsis, multisystem organ failure and even death. Leflunomide has important immunomodulatory and anti-inflammatory effects, which may mitigate host response to bacterial translocation. The goal of our study was to measure the effects leflunomide administration had on a variety of biochemical markers upregulated in systemic inflammatory response syndrome, sepsis, and multiple organ failure syndrome.
dc.identifier.citationOzturk E., Surucu M., Karaman A., ŞAMDANCI E., Fadillioglu E., -Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis-, JOURNAL OF SURGICAL RESEARCH, cilt.187, ss.610-615, 2014
dc.identifier.doi10.1016/j.jss.2013.11.005
dc.identifier.pubmed24484905
dc.identifier.scopus84900560681
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24266
dc.identifier.wosWOS:000332770600033
dc.titleProtective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id9a8daf7f-5d0b-426d-bdd7-3e63e9746637
local.publication.isinternational1
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