Person: İZZETTİN, FIKRET VEHBI
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Publication Metadata only Determination of CYP2C19 polymorphisms, adverse drug reaction, and medication adherence in patients utilized selective serotonin reuptake inhibitors(2015-02-01T00:00:00Z) Deniz, Semanur; SANCAR, MESUT; OKUYAN, BETÜL; ATA, PINAR; Bingol-Ozakpinar, Ozlem; TALAS, Anil; GUNES, Tufan; CALISKAN, Mecit; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of pharmacy technicians- attitudes and responsibilities toward patient oriented pharmacy practices at community pharmacy(2012-02-01T00:00:00Z) SANCAR, MERT; OKUYAN, BETÜL; Tamyuksel, E.; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of attitude and knowledge in patients utilized disposable insulin pens at community pharmacy setting(2016-04-01T00:00:00Z) OKUYAN, BETÜL; Semerci, Z.; Odabasi, G.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of individuals- knowledge and attitudes towards utilization of analgesics at community pharmacy setting(2019-02-01T00:00:00Z) Torun, B.; ÖZKAN, ONUR CAN; Zortul, H.; Kesedar, S.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIPublication Metadata only Impact of a pharmaceutical care program on glycemic control, medication knowledge and medication adherence levels of type 2 diabetic patients residing at a nursing home(2017-02-01T00:00:00Z) Saglam, Nimet; Apikoglu-Rabus, Sule; OKUYAN, BETÜL; Izzettin, Fikret V.; Yildirim, NURAN; İZZETTİN, FIKRET VEHBIPublication Metadata only Drug-drug interactions identified for cardiac transplant recipients(2017-02-01T00:00:00Z) Apikoglu-Rabus, Sule; RABUS, Murat B.; Ozkan, Oznur; ŞAHİN, YELİZ; Izzettin, Fikret V.; İZZETTİN, FIKRET VEHBIPublication Metadata only Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats(2017-09-01T00:00:00Z) Bami, Erliasa; Ozakpinar, Ozlem Bingol; Ozdemir-Kumral, Zarife Nigar; Koroglu, Kutay; ERCAN, FERİHA; CIRAKLI, Zeynep; ŞEKERLER, TURGUT; Izzettin, FİKRET VEHBİ; SANCAR, MESUT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIThis study aims to determine the potential protective effects of ferulic acid against cisplatin-induced nephrotoxicity and to compare its effect with curcumin, a well-known protective agent against cisplatin- induced toxicity in rats. Administration of cisplatin resulted in high BUN (Blood Urea Nitrogen), creatinine, MDA (Malondialdehyde), MPO (Myeloperoxidase), TOS (Total Oxidative Status), PtNT (Protein Nitrotyrosine) levels (p < 0.05). Histological observations showed abnormal morphology of kidney; in addition with appearance of TUNEL positive cells indicating apoptosis in cisplatin administered group. HO-1 (Heme Oxygenase-1) levels measured by RT-PCR (Real Time Polymerase Chain Reaction), and TAS (Total Antioxidative Status) revealed antioxidant depletion due to cisplatin toxicity in animals (p < 0.05). All parameters showed improvement in groups treated with ferulic acid (p < 0.05). Ferulic acid treatment was found significant in preventing oxidative stress, increasing antioxidative status and regaining histological parameters to normal, indicating nephroprotective and antioxidant effects of this phenolic compound.Publication Metadata only The role of the clinical pharmacist in patient education and monıtoring of patients under warfarin treatment(2019-01-01) İZZETTİN, FİKRET VEHBİ; SANCAR, MESUT; AKSOY, NİLAY; TEZCAN, SONGÜL; BEKTAY, MUHAMMED YUNUS; İZZETTİN, FIKRET VEHBI; BEKTAY, MUHAMMED YUNUSThis study was carried out on patients who were under anticoagulation treatment with warfarin, at the outpatient cardiology clinic. The aim was to determine the effectiveness of pharmacist consultation, education, and intervention on each patient-s therapeutic results. A cross-sectional randomized trial has been done. Twenty-five patients were included in the study. The Oral Anticoagulation Knowledge (OAK) Test, Short Form-36 (SF-36) and Duke Anticoagulation Satisfaction Scale (DASS) were applied. Patients resumed their routine anticoagulation treatment and INR and complications were recorded during the study. Additionally, patients received patient education, consultation on lifestyle and anticoagulant usage issues from a pharmacist. The same tests were applied again to the patients on the 90th day of the study and the results were compared with the initial test. Maintenance of INR within the target range and complication rates were compared before and after the intervention. Pre-test and post-test results of the patients revealed statistically significant improvements on the physical and mental score components of the SF-36 (p = 0.001; p = 0.001), OAK test scores (p <= 0.001) and the (negative) -limitations- and -burdens- and -positive effects- components of the DASS (p = 0.005; p < 0.001; p = 0.001). The successful maintenance of INR within target range was significantly higher (p = 0.027). The positive effects of pharmacist consultation and education on therapeutic results were demonstrated.Publication Metadata only Influence of Pharmacist Recommendations for Chemotherapy-Related Problems in Diabetic Cancer Patients(2017-01-01T00:00:00Z) Izzettin, Fikret V.; Al-taie, Anmar; SANCAR, MESUT; ALIUSTAOGLU, Mehmet; İZZETTİN, FIKRET VEHBIDrug related-problems pose additional worse outcomes in cancer patients treated with chemotherapy. A vital role of the clinical pharmacist is the detection and prevention of drug-related problems. The provision of patient education is an important step to reduce and prevent drug-related problems during chemotherapy administration. The objective of this study was to assess the occurrence of drug-related problems and the importance of effective provision of patient education and appropriate recommendations by the clinical pharmacist in reducing and solving of these problems in diabetic patients suffering from cancer.Publication Metadata only Characteristics of the drug-disease information service demanded from the community pharmacist(2011-04-01T00:00:00Z) APIKOGLU-RABUS, S.; Pakalpakcil, O.; OKUYAN, BETÜL; SANCAR, MERT; Soydeger-Carli, B.; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBI