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BAYRAM, MEHMET

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MEHMET
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BAYRAM
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    Evaluation of Patients with Behcet-s Disease Presenting with Pulmonary Symptoms
    (2011-12-01) OZKAN, Gulcihan; CAMSARI, Gungor; BAKAN, Dilek; Kiyan, Esen; Okumus, Gulfer; GUR, Aygun; Bayram, MEHMET; BAYRAM, MEHMET
    Objective: Behcet-s disease (BD) is a multisystem disorder and survival depends on pulmonary involvement, especially pulmonary artery aneurysm. Therefore early diagnosis and treatment of pulmonary involvement are very important. This study was conducted to evaluate clinical features, treatment results and outcome of patients with BD presenting with pulmonary symptoms. Material and Methods: Medical records of patients diagnosed as BD over a 17-years period from 1991 to 2008 who presented with pulmonary symptoms in two different chest clinics were reviewed retrospectively. Clinical and radiological findings, treatment and follow-up results were investigated. Results: Twenty-two patients (19 males, three females) diagnosed with BD were included. The mean age was 35.4 years. Sixteen of the patients (72.7%) were diagnosed with BD at chest clinics for first time. Main presenting pulmonary symptom was hemoptysis (72.7%) and six of them (27.3%) had massive hemoptysis. Thirteen patients (59%) had pulmonary artery aneurysms, five of them also had thrombosis within the aneurysm. Nineteen patients (86%) were administered immunosupressive therapy. Eighteen (81.8%) of the patients were followed, median follow-up time was four years. Thirteen patients responded to immunosuppressive therapy. Three patients (16.7%) died, two of them with massive hemoptysis. Conclusion: BD should be kept in mind in differential diagnosis of hemoptysis in young patients, especially in countries with high incidence of BD. Early diagnosis and aggressive treatment for pulmonary involvement can prevent a fatal outcome.
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    PublicationOpen Access
    [Relationship between symptoms of obstructive sleep apnea syndrome and traffic accidents in the city drivers].
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; KART, L; ULUDAĞ, M; Bayram, MEHMET; ALISHA, G; ÖZÇELIK, H; Karaköse, FATMANUR; SEZER, M; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Introduction: There is a high tendency for traffic accidents in patients with obstructive sleep apnea syndrome (OSAS). Thus it's recommended to investigate OSAS symptoms before certification of professional drivers. However, to what degree OSAS symptoms predict traffic accidents is not clear. We aimed to investigate the relationship between OSAS symptoms and traffic accidents. Materials and methods: Five hundred twenty bus drivers working at Istanbul Electricity, Tramway and Tunnel (IETT) general management were randomly selected. Berlin questionnaire was applied which included demographic data, accident ratios, total duration in profession, duration of working in a day and OSAS symptoms. Epworth sleepiness score (ESS) test was applied to assess day time slepiness. Results: All drivers were male. Snoring were present in 324 (65.7%) of participants. Traffic accident history were present in 259 (49.7%) of drivers. Significant relationship was present between traffic accident and only daytime sleepiness among the OSAS symptoms. The mean of accident/year ratio of all participants were 0.092. Mean of ESS was 7.3 ± 3.2 for all participants. There is a positive correlation between ESS and accident/year ratio (r= 0.57, p= 0.012). Conclusion: Only daytime sleepiness among OSAS symptoms is related with traffic accident. The questioning of OSAS symptoms alone is inadequate to estimate traffic accident risk. Thus further consideration more than symptom questioning is needed at phase of authorization of professional drivers to detect OSAS.
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    Environmental exposure to asbestos: from geology to mesothelioma
    (2014-05-01) Bayram, MEHMET; Bakan, Nur Dilek; BAYRAM, MEHMET
    Purpose of reviewThis article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos.Recent findingsWith the motion of continental and oceanic plates, in some parts of the world serpentinites in the lower layer of the oceanic plate move into the continental plate and form the so-called ophiolites. Ophiolites consist of soil and rocks containing serpentine-type asbestos. There is an increase in ARDs in regions close to ophiolites. Indoor exposure and outdoor exposure to NOA, outdoor exposure to industrial asbestos and mines, urbanization and construction works in NOA regions are the known sources and types of environmental asbestos exposure.SummaryAlthough there is an expectance of decline in ARDs caused by industrial exposure to asbestos, the environmental exposure to asbestos is still a challenge waiting to be overcome.
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    PublicationOpen Access
    Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study
    (2015-05-01) BAKAN, Mefkur; UMUTOGLU, Tarik; TOPUZ, Ufuk; UYSAL, HARUN; Bayram, MEHMET; Kadioglu, HÜSEYİN; SALIHOGLU, Ziya; UYSAL, HARUN; BAYRAM, MEHMET; KADIOĞLU, HÜSEYİN
    Justificativa e objetivos: O uso de opioides no período intraoperatório pode estar associado à hiperalgesia e ao aumento do consumo de analgésicos no período pós-operatório. Efeitos colaterais como náusea e vômito no período pós-operatório, por causa do uso perioperatório de opioides, podem prolongar a alta. Nossa hipótese foi que a anestesia venosa total com o uso de lidocaína e dexmedetomidina em substituic¸ão a opioides pode ser uma técnica opcional para a colecistectomia laparoscópica e estaria associada a uma menor solicitac¸ão de fentanil e incidência de náusea e vômito no período pós-operatório. Métodos: Foram programados para colecistectomia laparoscópica eletiva 80 pacientes adultos, estado físico ASA I-II. Os pacientes foram randomicamente alocados em dois grupos para receber anestesia livre de opioides com infusões intravenosas (IV) de dexmedetomidina, lidocaína e propofol (Grupo DL) ou anestesia baseada em opioides com infusões de remifentanil e propofol (Grupo RF). Todos os pacientes receberam um regime padrão de analgesia multimodal. Um dispositivo de analgesia controlada pelo paciente foi ajustado para liberar fentanil IV por seis horas após a cirurgia. O desfecho primário foi o consumo de fentanil no pós-operatório. Resultados: O consumo de fentanil na segunda hora de pós-operatório foi significativamente menor no grupo DL do que no Grupo RF, 75 ± 59g e 120 ± 94g, respectivamente, mas foi comparável na sexta hora de pós-operatório. Durante a anestesia, houve mais eventos hipotensivos no Grupo RF e mais eventos hipertensivos no grupo DL, ambos estatisticamente significativos. Apesar de apresentar um tempo de recuperac¸ão mais prolongado, o Grupo DL apresentou escores de dor e consumo de analgésicos de resgate e de ondansetrona significativamente mais baixos
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    PublicationOpen Access
    [The frequency and properties of REM related obstructive sleep apnea among the patients with mild related obstructive sleep apnea].
    (2013-01-01) Kutbay, Özçelik; Akkoyunlu, MUHAMMED EMİN; BOSTANLı, P; Bayram, MEHMET; ATAHAN, E; SEZER, M; Karaköse, FATMANUR; KART, L; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Hafif obstrüktif uyku apneli hastalarda REM ile ilişkili obstrüktif uyku apne sıklığı ve özellikleri Giriş: REM ile ilişkili obstrüktif uyku apne (OUA), “Hafif ve orta OUA olgularında daha fazla görülmesi nedeniyle uykuda solunum bozuklukları spektrumunun erken bir işareti midir?” yoksa “Tamamen ayrı bir antite midir?” sorusuyla araştırmacıların son zamanlarda oldukça dikkatini çekmektedir. Bu çalışmada, hafif OUA tanılı hastalar arasında REM ile ilişkili OUA hastalarının sıklığını ve diğer hafif OUA tanılı hastalardan farkını görmek; ayrıca REM ile ilişkili OUA hastalarında gündüz aşırı uykululuk ile apne ilişkisini değerlendirmek amaçlanmıştır. Materyal ve Metod: 1 Ağustos 2010 ile 29 Şubat 2012 tarihleri arasında Bezmialem Vakıf Üniversitesi Uyku Laboratuvarında polisomnografi tetkiki yapılan toplam 1267 hasta arasından, 134 hafif OUA [Apne hipopne indeksi (AHİ)= 5-15] tanılı hasta retrospektif olarak değerlendirildi. REM AHİ/non-REM AHİ ≥ 2 olan ve non-REM AHİ < 15 olanlar; REM ile ilişkili OUA olarak kabul edildi. Bulgular: Toplam 134 hafif OUA tanılı hastadan 80 (%59)’i REM ile ilişkili OUA olarak değerlendirildi. REM ilişkili OUA ve diğer hafif OUA’lılar yaş, cinsiyet, gündüz aşırı uykululuk, beden kitle indeksi, boyun çevresi ve ek hastalık varlığı açısından karşılaştırıldığında; REM ile ilişkili OUA grubunda yalnızca yaş ortalaması anlamlı olarak düşük bulundu. REM ile ilişkili OUA grubunun %87.3’ünde REM AHİ 15’in üzerinde; %39.3’ünde 30’un üzerindeydi. REM ile ilişkili OUA olgularında; REM AHİ ile gündüz aşırı uykululuk semptomu arasında anlamlı ilişki saptanmadı (p= 0.81). Sonuç: Hafif OUA olguları arasında, REM ile ilişkili OUA grubunun yaş ortalamasının daha düşük olması, REM OUA’nın “uykuda solunum bozuklukları spektrumunun erken bir işareti” olabileceğini düşündürebilir. Bu grup hastaların klinik takibinin bu sorunun cevabı açısından yararlı olacağı kanısındayız.
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    Does CPAP treatment lead to gastroesophageal reflux in moderate and severe OSA case.
    (2014-09-01) OZCELIK, Hatice Kutbay; DANALIOGLU, Ahmet; Bayram, MEHMET; Akkoyunlu, MUHAMMED EMİN; YAKAR, Fatih; KARAKOSE, Fatmanur; SEZER, Murat; BAYRAM, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR
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    Asbestos-Related Diseases in Turkey: Not Only Caused by Naturally Occurring Fibers, but Also by Industrial Exposures
    (2018-12-01) Mehmdi, Elnur; BAYRAM, MEHMET; ÖZKAN, DİDEM; Bilgin, Sabriye Şennur; BİLGİN, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR; KANSU, ABDULLAH; BAYRAM, MEHMET; ÖZKAN, DİDEM; HAYAT, ESAT; BİLGİN, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR; KANSU, ABDULLAH
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    Ultrasound guided fine-needle aspiration biopsy of metastases in nonpalpable supraclavicular lymph nodes in lung cancer patients
    (2011-08-01) KENDIRLINAN, Resat; OZKAN, Gulcihan; Bayram, MEHMET; Bakan, Nur Dilek; TUTAR, Mehmet; GUR, Aygun; CAMSARI, Gungor; BAYRAM, MEHMET
    Background and objectives: To assess frequency and significance of enlarged nonpalpable supraclavicular lymph nodes with routine ultrasound (US) evaluation and US-guided fine-needle aspiration biopsy (FNAB) for the diagnosis and staging of patients with lung cancer.
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    COPD: an underdiagnosed disease at hospital environment
    (2014-02-01) Kart, Levent; Akkoyunlu, MUHAMMED EMİN; Bayram, MEHMET; YAKAR, Fatih; OZCELIK, Hatice Kutbay; KARAKOSE, Fatmanur; SEZER, Murat; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Background and Aim Chronic obstructive pulmonary disease (COPD) is a serious disease with morbidity and mortality due to delayed diagnosis until significant symptoms arise. We aimed to assess the utility of spirometry and COPD Assessment Test (CAT) in detecting undiagnosed COPD patients in a localized area.