Person: TOK, OLGU ENİS
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Publication Metadata only The Effect of Apelin on Podocytes in Doxorubicin Induced Nephrotic Syndrome.(2017-05-21) Özkan, Naziye; SEHIRLI, AHMET OZER; Yüksel, Meral; Çilingir, Özlem Tuğçe; TOK, OLGU ENİS; Aydemir, Sezgin; Koç, Mehmet; CETINEL, SULE; TOK, OLGU ENİSPublication Metadata only Shea Yağının Yara İyileşmesi Üzerine Etkisi.(2016-05-03) BAYINDIR, NİHAN; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDES; Kılıç, Elif; BULUT, HURİ; BAYINDIR, NİHAN; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDES; BULUT, HURIPublication Metadata only Electromagnetic Waves Emitted By Mobile Phones Effect On The Testis Morphology Of Rat, Cell Death and Blood-Testis Barrier: Evaluation for Infertility.(2014-09-12) TOK, OLGU ENİS; SEHIRLI, AHMET OZER; ERCAN, FERIHA; TOK, OLGU ENİSPublication Metadata only Cep Telefonları Kaynaklı Elektromanyetik Dalgaların Sıçan Trigeminal Siniri Üzerine Etkileri(2016-05-03) Akakın, Dilek; TOK, OLGU ENİS; Dağbaşı, Nükhet; Anıl, Damla; Akakın, Akın; Şirvancı, Serap; ERCAN, FERIHA; TOK, OLGU ENİSPublication Metadata only Genç Ve Yaşlı Sprague-Dawley Sıçanlarda Parsiyel Hepatektomi Sonrası Melatoninin Karaciğer Rejenerasyonuna Etkisi.(2016-05-03) TOK, OLGU ENİS; AYDIN, M. S.; ESREFOGLU, MUKADDES; IRAZ, M.; KESKİN, Sıdıka; KOÇYİĞİT, ABDÜRRAHİM; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDES; KOÇYİĞİT, ABDÜRRAHİMPublication Metadata only Expression patterns of F-Actin and Nanog, an embryonic stem cell marker, in monolayer and spheroid culture of human liver carcinoma cell line.(2014-12-01) Aktas, R. G.; Tok, OLGU ENİS; TOK, OLGU ENİSPublication Metadata only Dose Dependent Effects of Dimethyl Sulfoxide on the Mitochondria of Hepatocellular Carcinoma Cells(2016-01-01) Aktas, R. G.; Isan, H.; Caliskan, E. B.; Tok, OLGU ENİS; AYDIN, M. S.; KAYA, ÖZLEM TUĞÇE; TOK, OLGU ENİSPublication Metadata only Correlation between the mechanical and histological properties of liver tissue(2014-01-01) Yarpuzlu, Berkay; Ayyildiz, Mehmet; Tok, OLGU ENİS; Aktas, Ranan Gulhan; Basdogan, Cagatay; TOK, OLGU ENİSIn order to gain further insight into the mechanisms of tissue damage during the progression of liver diseases as well as the liver preservation for transplantation, an improved understanding of the relation between the mechanical and histological properties of liver is necessary. We suggest that this relation can only be established truly if the changes in the states of those properties are investigated dynamically as a function of post mortem time. In this regard, we first perform mechanical characterization experiments on three bovine livers to investigate the changes in gross mechanical properties (stiffness, viscosity, and fracture toughness) for the preservation periods of 5, 11, 17, 29, 41 and 53 h after harvesting. Then, the histological examination is performed on the samples taken from the same livers to investigate the changes in apoptotic cell count, collagen accumulation, sinusoidal dilatation, and glycogen deposition as a function of the same preservation periods. Finally, the correlation between the mechanical and histological properties is investigated via the Spearman-s Rank-Order Correlation method. The results of our study show that stiffness, viscosity, and fracture toughness of bovine liver increase as the preservation period is increased. These macroscopic changes are very strongly correlated with the increase in collagen accumulation and decrease in deposited glycogen level at the microscopic level. Also, we observe that the largest changes in mechanical and histological properties occur after the first 11-17 h of preservation. (C) 2013 Elsevier Ltd. All rights reserved.Publication Metadata only Uzun Süreli ve Düşük Doz Siklosporin Kullanımının Böbrek Dokusu Üzerine Apopitotik Etkileri(2014-03-09) Garip, Aylin; Uzak, Emirhan; TOK, OLGU ENİS; ESREFOGLU, MUKADDES; AKTAS, R. G.; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDESPublication Metadata only Effects of beta-glucan on protection of young and aged rats from renal ischemia and reperfusion injury(2016-01-01) ESREFOGLU, MUKADDES; Tok, OLGU ENİS; AYDIN, M. S.; OZER, O. F.; SELEK, S.; Iraz, M.; EŞREFOĞLU, MUKADDES; TOK, OLGU ENİS; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİNBACKGROUND: Ischemia reperfusion injury is one of the leading causes of acute renal failure which is a common clinical event leading to development of chronic kidney disease and a high mortality; especially in elderly people. beta-glucans are glucose polymer groups with free-radical scavenger, macrophage activator, and immune defense inducer functions. We designed this study to determine the possible protective effects of beta-glucan against renal ischemia reperfusion injury comparatively in young and aged rats.
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