Dose and time dependent ototoxicity of aspartame in rats
SJOSTRAND, Alev Pektas
Yildirim, YAVUZ SELİM
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Conclusion: Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased.