• Home
  • About
  • Policies
  • Contact
    • English
    • Türkçe
  • English 
    • English
    • Türkçe
  • Login
Advanced Search
View Item 
  •   Home
  • Tüm Akademik Yayınlar
  • Yayınlar - Eserler
  • View Item
  •   Home
  • Tüm Akademik Yayınlar
  • Yayınlar - Eserler
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Elevated beta-thromboglobulin and mean platelet volume levels may show persistent platelet activation in systemic lupus erythematosus patients.

Thumbnail
View/Open
91-Elevated beta-thromboglobulin and mean platelet volume levels may show persistent platelet activation in systemic lupus erythematosus patients..pdf (141.4Kb)
Date
2018-09-01
Author
MENGÜÇ, MU
Karatoprak, CUMALİ
DEMIRTUNÇ, R
DOLU, S
ABANONU, GB
PEHLEVAN, SM
DAŞKIN, A
UYAR, S
Advisor
Type
Article
Metadata
Show full item record
Abstract
Background. Patients with systemic lupus erythematosus (SLE) have anincreased risk of thrombotic events. Platelets become more active and they enlarge torelease proteins from alpha granules for aggregation during the plaque formation period. Beta-thromboglobulin isone of the proteins released from alpha-granules when platelets are activated and used as a marker ofplatelet activation invivo. Objectives. The aim of this study was to evaluate the plasma levels of beta-thromoglobulin and mean platelet volume as markers of the presence ofplatelet activation insystemic lupus erythematosus patients compared with healthy controls. Material and methods. Thirty-seven SLE patients with a mean disease duration of4.96years and without any organ involvement as well as 30 healthy volunteers were included in the study. All patients were inremission ofSLE. Results. Themean beta-thromboglobulin level was 97.36±55.8ng/mL inthe SLE group and 72.67±33.5ng/mL inthe control group (p = 0.029). The mean platelet volume level was 8.27 ±1.68 fL inthe SLE group and 9.16 ±1.52 fL (p = 0.031) inthe controls. Conclusions. Elevated beta-thromboglobulin levels in systemic lupus erythematosus patients may be associated with platelet activation inthe early stages ofdisease, whereas lower mean platelet volume levels inthe same population may be due tothe effects ofhydroxychloroquine and the inactivity ofSLE.
Subject
UYAR S., ABANONU G., PEHLEVAN S., Karatoprak C., MENGÜÇ M., DAŞKIN A., DOLU S., DEMIRTUNÇ R., -Elevated beta-thromboglobulin and mean platelet volume levels may show persistent platelet activation in systemic lupus erythematosus patients.-, Advances in clinical and experimental medicine : official organ Wroclaw Medical University, cilt.27, ss.1279-1283, 2018
URI
https://hdl.handle.net/20.500.12645/3973
Collections
  • PubMed İndeksli Yayın Koleksiyonu [3700]
  • Scopus İndeksli Yayınlar Koleksiyonu [4458]
  • Tıp Fakültesi [2546]
  • WoS İndeksli Yayınlar Koleksiyonu [5222]
  • Yayınlar - Eserler [10057]

BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS


Bezmialem Kütüphane


OpenAccess@BVU validated by OpenAIRE

sherpa/romeo

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypeLanguageRightsby AdvisorThis CollectionBy Issue DateAuthorsTitlesSubjectsTypeLanguageRightsby Advisor

My Account

LoginRegister

BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS