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High Levels of Serum Uric Acid Impair Development of Coronary Collaterals in Patients With Acute Coronary Syndrome

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2012-08-01T00:00:00Z
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Duran, Mustafa
Ornek, Ender
Murat, Sani N.
Turfan, Murat
Vatankulu, Mehmet A.
Ocak, Ayse
Doger, Cihan
Yalcin, Ahmet A.
Demircelik, Muhammed B.
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Abstract
We evaluated the association of serum uric acid (SUA) level and development of coronary collateral vessels (CCVs) in patients with acute coronary syndrome (ACS). Patients (n = 224) with ACS were included in the study. Coronary collateral vessels were graded according to the Rentrop scoring system. Rentrop grade 0 was accepted as absence of CCV (group >= 1; n = 117) and Rentrop grade ayen1 was accepted as presence of CCV (group 2; n = 107). Rentrop 0-1 (poor CCV) were determined in 167 patients and Rentrop 2-3 (good CCV) were determined in 57 patients. Both presence of CCV (P < .001) and development of good CCV (P = .003) were significantly associated with low levels of SUA. We suggest that high levels of SUA affect the CCV development negatively in nondiabetic and nonhypertensive patients with ACS.
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Duran M., Ornek E., Murat S. N. , Turfan M., Vatankulu M. A. , Ocak A., Doger C., Yalcin A. A. , Demircelik M. B. , -High Levels of Serum Uric Acid Impair Development of Coronary Collaterals in Patients With Acute Coronary Syndrome-, ANGIOLOGY, cilt.63, ss.472-475, 2012
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