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Prevalence of erectile dysfunction in patients with chronic kidney disease: a systematic review and meta-analysis.

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dc.contributor.authorPizzol, D
dc.contributor.authorXiao, T
dc.contributor.authorYang, L
dc.contributor.authorDemurtas, J
dc.contributor.authorMcDermott, D
dc.contributor.authorGarolla, A
dc.contributor.authorNardelotto, A
dc.contributor.authorGrabovac, I
dc.contributor.authorKazancioglu, Rümeyza
dc.contributor.authorVeronese, N
dc.contributor.authorSmith, L
dc.contributor.institutionauthorSOYSAL, PINAR
dc.contributor.institutionauthorKAZANCIOĞLU, RÜMEYZA
dc.date.accessioned2020-05-04T20:59:09Z
dc.date.available2020-05-04T20:59:09Z
dc.date.issued2020-05-01T00:00:00Z
dc.description.abstractGrowing evidence reports that chronic kidney diseases (CKD) might play a role in erectile dysfunction (ED), but limited knowledge is available. Therefore, we performed a systematic review up to 21/08/2019 to investigate the associations between CKD and ED. The main analysis reported the prevalence of ED as absolute estimates (in %) with their 95% confidence intervals (CIs) and across CKD stages (when specified), hemodialysis and transplant, calculating the p for interaction across strata. Among 291 studies, we included 34 articles with 5986 men. We found an overall prevalence of 76% (95%CI: 72-79) with a high degree of heterogeneity (I2 = 84.2%; p < 0.0001). Analyzing the data by CKD stage, we found a significant higher prevalence of ED in CKD (78%; 95%CI: 75-81%; I2 = not possible) compared with hemodialysis stage (prevalence = 77%; 95%CI: 73-80%; I2 = 84.5) or to patients undergoing transplant (prevalence = 64%; 95%CI: 54-74%; I2 = 54%) (p across strata = 0.036). Considering the high prevalence of ED in men with CKD, health care practitioners should focus on issues of sexual health in men with CKD. Given the advancements in dialysis and therapy and the associated advancements in survival and life expectancy, maintaining the patients' sexual function is important for their well-being and quality of life.en
dc.identifier.citationPizzol D., Xiao T., Yang L., Demurtas J., McDermott D., Garolla A., Nardelotto A., Grabovac I., Soysal P., Kazancioglu R., et al., -Prevalence of erectile dysfunction in patients with chronic kidney disease: a systematic review and meta-analysis.-, International journal of impotence research, 2020
dc.identifier.doi10.1038/s41443-020-0295-8
dc.identifier.pubmed32358511
dc.identifier.urihttps://hdl.handle.net/20.500.12645/17967
dc.identifier.urihttps://www.nature.com/articles/s41443-020-0295-8
dc.language.isoen
dc.subjectErectile dysfunctionen
dc.subjectChronic kidney diseaseen
dc.titlePrevalence of erectile dysfunction in patients with chronic kidney disease: a systematic review and meta-analysis.
dc.typeArticle
dspace.entity.typePublication
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local.publication.isinternational1
relation.isAuthorOfPublication0e36986e-d71d-4579-a395-877af097ade5
relation.isAuthorOfPublicationeca7bd30-6b6e-444d-96ae-2961c39f2107
relation.isAuthorOfPublication.latestForDiscovery0e36986e-d71d-4579-a395-877af097ade5
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