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Electrochemical biosensor based on REGO/Fe3O4 bionanocomposite interface for xanthine detection in fish sample

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dc.contributor.advisor
dc.contributor.authorDervisevic, Muamer
dc.contributor.authorCustiuc, Esma
dc.contributor.authorCevik, Emre
dc.contributor.authorDurmus, ZEHRA
dc.contributor.authorSenel, Mehmet
dc.contributor.authorDurmus, Ali
dc.date.accessioned2019-10-05T21:54:30Z
dc.date.available2019-10-05T21:54:30Z
dc.date.issued2015-11-01
dc.description.abstractIn this study, xanthine molecules which can serve as an indicator of meat spoilage were determined using a novel and sensitive amperometric xanthine biosensor. Biosensor was developed by preparing a nanocomposite film that was constructed by embedding reduced expanded graphene oxide (REGO) sheets decorated with iron oxide (Fe3O4) nanoparticles into poly(glycidyl methacrylate-covinylferrocene) (P(GMA-co-VFc)) phase, and by covalent immobilization of Xanthine oxidase (XOD) on the surface of P(GMA-co-VFc)/REGO-Fe3O4 nanocomposite film. Bio-analytical optimal experimental conditions such as response time, linear range, operation and storage stability, working pH and temperature were studied. Current response of linear range was detected in the range of 2-36 mu M with a sensitivity of 0.17 mu A/M, response time of similar to 3 s, and detection limit of 0.17 mu W. The resulting bionanocomposite xanthine biosensor was subjected to fish real sample testings where 5, 8, 10, 13, 15, and 20 days-old fish samples- xanthine content was measured. The developed biosensor was found to be applicable to real samples as a very reliable fish freshness controlling technique. (C) 2015 Elsevier Ltd. All rights reserved.
dc.description.sponsorshipBezmiâlem Vakıf Üniversitesi
dc.identifier
dc.identifier.citationDervisevic M., Custiuc E., Cevik E., Durmus Z., Senel M., Durmus A., -Electrochemical biosensor based on REGO/Fe3O4 bionanocomposite interface for xanthine detection in fish sample-, FOOD CONTROL, cilt.57, ss.402-410, 2015
dc.identifier.doi10.1016/j.foodcont.2015.05.001
dc.identifier.scopus84929318794
dc.identifier.urihttps://hdl.handle.net/20.500.12645/8419
dc.identifier.wosWOS:000357839100059
dc.language.isoen
dc.titleElectrochemical biosensor based on REGO/Fe3O4 bionanocomposite interface for xanthine detection in fish sample
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF MOOD DISORDERS
local.avesis.idd1e81625-bcc5-4e40-9d53-bc1d92de03a2
local.avesis.response8295
local.publication.isinternational1
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