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Visfatin levels in gingival crevicular fluid and serum before and after non-surgical treatment for periodontal diseases

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dc.contributor.authorTurer, Cigdem Coskun
dc.contributor.authorBalli, UMUT
dc.contributor.authorGuven, Berrak
dc.contributor.authorCetinkaya, Burcu Ozkan
dc.contributor.authorKeles, Gonca Cayir
dc.contributor.institutionauthorBALLI, UMUT
dc.date.accessioned2021-02-01T20:59:25Z
dc.date.available2021-02-01T20:59:25Z
dc.date.issued2016-12-01T00:00:00Z
dc.description.abstractThe purpose of this study was to evaluate visfatin levels at different stages of periodontal disease and in healthy tissues. In addition, the effect of non-surgical periodontal therapy on visfatin levels in gingival crevicular fluid and serum was investigated. Forty-five patients were divided into three groups based on clinical and radiographical findings. Group I comprised periodontally healthy individuals (n = 15); group 2 comprised patients with gingivitis (n = 15); and group 3 was composed of patients with generalized chronic periodontitis (n = 15). Gingival crevicular fluid and serum samples were collected before treatment and at 1, 3, and 6 months after treatment. Visfatin levels were measured by enzyme linked immunosorbent assays. Gingival crevicular fluid and serum visfatin levels were higher in patients with chronic periodontitis than those with gingivitis or healthy controls (P < 0.016). In addition, visfatin levels were higher in the gingivitis group than in healthy controls (P < 0.016). Non-surgical periodontal treatment resulted in a significant reduction in gingival crevicular fluid and serum visfatin levels. Furthermore, visfatin levels increased with inflammation and decreased following periodontal treatment. Our findings suggest that visfatin is an inflammatory biomarker of periodontal disease.
dc.identifier.citationTurer C. C. , Balli U., Guven B., Cetinkaya B. O. , Keles G. C. , -Visfatin levels in gingival crevicular fluid and serum before and after non-surgical treatment for periodontal diseases-, JOURNAL OF ORAL SCIENCE, cilt.58, ss.491-499, 2016
dc.identifier.doi10.2334/josnusd.16-0116
dc.identifier.scopus85007310509
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28234
dc.identifier.wosWOS:000390087600006
dc.titleVisfatin levels in gingival crevicular fluid and serum before and after non-surgical treatment for periodontal diseases
dc.typeArticle
dspace.entity.typePublication
local.avesis.id41c7acae-47c6-4232-8778-6f91a4cc29d6
local.publication.isinternational1
relation.isAuthorOfPublication98da5869-ea4b-40c5-873f-9bbd29c50a23
relation.isAuthorOfPublication.latestForDiscovery98da5869-ea4b-40c5-873f-9bbd29c50a23
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