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RELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND MYELOPEROXIDASE AND CATALASE ACTIVITIES AND THIOL LEVELS

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dc.contributor.authorCamli, AHMET ADİL
dc.contributor.authorTAŞPINAR, ÖZGÜR
dc.contributor.authorAydin, TEOMAN
dc.contributor.authorKEPEKÇİ, MÜGE
dc.contributor.authorOzer, O. F.
dc.contributor.authorKeskin, YAŞAR
dc.contributor.authorSelek, S.
dc.contributor.authorMutluer, A. S.
dc.contributor.institutionauthorÇAMLI, AHMET ADİL
dc.contributor.institutionauthorAYDIN, TEOMAN
dc.contributor.institutionauthorÖZER, ÖMER FARUK
dc.contributor.institutionauthorSELEK, ŞAHABETTİN
dc.date.accessioned2019-10-05T14:27:07Z
dc.date.available2019-10-05T14:27:07Z
dc.date.issued2016-01-01
dc.description.abstractThe aim of this study is to evaluate myeloperoxidase activity, catalase activity and thiol levels at early with rheumatoid arthritis patients. Blood taken from the patients was diagnosed with RA according to American Rheumatism Association ACR 2010 criteria, but not employed the medication of DMARD (Disease-modifying antirheumatic drugs) in order to examine the antioxidant parameters of myeloperoxidase activity, catalase activity and thiol levels. Twenty nine patients with early RA and 61 healthy controls were included in the study. Peripheral blood samples were used for all the assays. The average age of the patients was 39.91 +/- 13.32 and their average BMI was 28.56 +/- 4.15. Erytrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values have been found significantly high levels in RA group when we compare with control group. Catalase activity and thiol levels which means antioxidant parameters, have been found significantly low levels according to control group. When the parameters of myeloperoxidase activity were compared to the control group, the values of control group were significantly high. Stronger response in patients with early RA suggests that antioxidant markers may be useful in evaluating the progression of RA as well as in elucidating the mechanisms of disease pathogenesis.
dc.identifier10.1097/wnf.0b013e31824c1c3f
dc.identifier.citationCamli A. A. , TAŞPINAR Ö., Aydin T., KEPEKÇİ M., Ozer O. F. , Keskin Y., Selek S., Mutluer A. S. , -RELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND MYELOPEROXIDASE AND CATALASE ACTIVITIES AND THIOL LEVELS-, OXIDATION COMMUNICATIONS, cilt.39, ss.3050-3057, 2016
dc.identifier.scopus85018397563
dc.identifier.urihttps://hdl.handle.net/20.500.12645/3922
dc.identifier.wosWOS:000392409100022
dc.language.isoen
dc.titleRELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND MYELOPEROXIDASE AND CATALASE ACTIVITIES AND THIOL LEVELS
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameClinical neuropharmacology
local.avesis.id5f4ba7b5-59df-475c-853b-ce067179bdd4
local.avesis.response3792
local.org.facultyTıp Fakültesi
local.publication.isinternational1
relation.isAuthorOfPublicationca17c745-9915-47c0-8887-702bfb63d86e
relation.isAuthorOfPublicationb499e019-3329-4b74-903c-dbbf64b9c18d
relation.isAuthorOfPublicationf5267834-a664-4da6-89f3-ae19762e1423
relation.isAuthorOfPublication8eb7d539-8ea4-435c-830e-8ef630342c7d
relation.isAuthorOfPublication.latestForDiscovery8eb7d539-8ea4-435c-830e-8ef630342c7d
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