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Current Concepts in the Diagnosis, Pathophysiology, and Treatment of Delirium: A European Perspective

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dc.contributor.authorSoysal, PINAR
dc.contributor.authorKaya, Derya
dc.contributor.authorIsik, Ahmet Turan
dc.contributor.institutionauthorSOYSAL, PINAR
dc.date.accessioned2020-10-29T21:40:58Z
dc.date.available2020-10-29T21:40:58Z
dc.date.issued2015-12-01T00:00:00Z
dc.description.abstractDelirium is a complex syndrome defined as an acute, fluctuating syndrome of altered attention, awareness, and cognition. Delirium is common in the elderly, but unfortunately underdiagnosed. The consequences could be significant such as an increase in mortality, hospitalization, loss of autonomy, and increased risk to be institutionalized. The predisposing and precipitating factors are well known, but the pathogenesis is not yet identified clearly. However, evidence that delirium is a neurotoxic factor which develops due primarily to neurotransmitter (cholinergic insufficiency) and inflammatory (increase in stress response/neuroinflammation) mechanisms is increasing each passing day. Delirium is associated with serious complications, but can also be treatable if diagnosed early and managed properly. It is important to develop primary and secondary prevention and therefore close contact with the patient, ensuring adequate vision, hearing, nutrition, hydration, and sleep; informing the caregivers about delirium for recognizing early symptoms of delirium, mobilizing the patient as early as possible, and managing the pain are strongly recommended. Besides, clinicians must identify the real underlying medical conditions. If non-pharmacologic interventions are insufficient, pharmacologic therapy should be implemented.
dc.identifier.citationSoysal P., Kaya D., Isik A. T. , -Current Concepts in the Diagnosis, Pathophysiology, and Treatment of Delirium: A European Perspective-, CURRENT GERIATRICS REPORTS, cilt.4, ss.284-289, 2015
dc.identifier.doi10.1007/s13670-015-0142-9
dc.identifier.scopus84945538768
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26375
dc.identifier.wosWOS:000218596000002
dc.titleCurrent Concepts in the Diagnosis, Pathophysiology, and Treatment of Delirium: A European Perspective
dc.typeArticle
dspace.entity.typePublication
local.avesis.id95fb16ee-4b7e-4a3e-a64f-21cf34ba0cd1
local.publication.isinternational1
relation.isAuthorOfPublication0e36986e-d71d-4579-a395-877af097ade5
relation.isAuthorOfPublication.latestForDiscovery0e36986e-d71d-4579-a395-877af097ade5
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