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A Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain

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dc.contributor.authorYilmaz, Anil
dc.contributor.authorCaglar, Pinar
dc.contributor.authorDirmenci, Tuncay
dc.contributor.authorGoren, Nezhun
dc.contributor.authorTopcu, GÜLAÇTI
dc.contributor.institutionauthorTOPÇU, GÜLAÇTI
dc.date.accessioned2019-10-05T14:37:46Z
dc.date.available2019-10-05T14:37:46Z
dc.date.issued2012-06-01
dc.description.abstractFrom the dichloromethane extract of Nepeta sorgerae, the isolation and structure elucidation are now reported of a new isopimarane diterpenoid, named sorgerolone, and two known triterpenoids, oleanolic acid and ursolic acid. Antioxidant activity of the extracts and the isolated terpenoids was determined by the DPPH free radical scavenging and lipid peroxidation inhibition (beta-carotene bleaching) methods. Anticholinesterase activity of the extracts and isolates was investigated by Ellman-s method against AChE and BChE enzymes. Although the antioxidant activity results were low, the AChE enzyme inhibition of the extracts and terpenoids was very promising.
dc.identifier10.1016/j.ijporl.2006.03.005
dc.identifier.citationYilmaz A., Caglar P., Dirmenci T., Goren N., Topcu G., -A Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain-, NATURAL PRODUCT COMMUNICATIONS, cilt.7, ss.693-696, 2012
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4325
dc.language.isoen
dc.titleA Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameINTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
local.avesis.id69689e1b-2803-4454-ae39-0a022947cae7
local.avesis.response4195
local.publication.goal15 - Karasal Yaşam
relation.isAuthorOfPublication3c94748e-c303-4294-ad67-c5a0739628e5
relation.isAuthorOfPublication.latestForDiscovery3c94748e-c303-4294-ad67-c5a0739628e5
relation.isGoalOfPublicationdc5278a1-996b-492e-912e-dae2534f10f4
relation.isGoalOfPublication.latestForDiscoverydc5278a1-996b-492e-912e-dae2534f10f4
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