Publication:
A variety of gene polymorphisms associated with idiopathic granulomatous mastitis

dc.contributor.authorDestek, SABAHATTİN
dc.contributor.authorGul, Vahit Onur
dc.contributor.authorAhioglu, Serkan
dc.contributor.institutionauthorDESTEK, SABAHATTİN
dc.date.accessioned2020-10-22T21:39:51Z
dc.date.available2020-10-22T21:39:51Z
dc.date.issued2016-09-01T00:00:00Z
dc.description.abstractIdiopathic granulomatous mastitis (IGM) is a rare and chronic inflammatory disorder. IGM mimics breast cancer regarding its clinical and radiological features. Etiology of IGM remains unclarified. Our patient was 37-year-old and 14 weeks pregnant. There was pain, redness and swelling in the right breast. The mass suggestive of malignancy was detected in sonography. Serum CA 125 and CA 15-3 levels were high. Genetic analysis was performed for the etiology. methylenetetrahydrofolate reductase (MTHFR) C 677 TT, beta-fibrinogen-455 G>A, plasminogen activator inhibitor (PAI)-1 5 G/5 G, angiotensin-converting enzyme (ACE) I/D mutation was found. IGM was diagnosed by cor biopsy. An association was also reported between breast cancer and mutations in MTHFR-C 677 T, PAI-1, ACE genes. Genetic polymorphisms may involve in the development of IGM as it was seen in our case. Further studies should be conducted to better clarify this plausible association.
dc.identifier.citationDestek S., Gul V. O. , Ahioglu S., -A variety of gene polymorphisms associated with idiopathic granulomatous mastitis-, JOURNAL OF SURGICAL CASE REPORTS, 2016
dc.identifier.doi10.1093/jscr/rjw156
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24961
dc.identifier.wosWOS:000385867900007
dc.titleA variety of gene polymorphisms associated with idiopathic granulomatous mastitis
dc.typeArticle
dspace.entity.typePublication
local.avesis.idfadc10b3-c9ff-49a7-8055-2bb6f55898aa
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication6510863e-f993-4bd8-af2c-8597f426b0e1
relation.isAuthorOfPublication.latestForDiscovery6510863e-f993-4bd8-af2c-8597f426b0e1
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
Files
Collections