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Value of ABO blood group in predicting the severity of children with Crimean-Congo hemorrhagic fever

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dc.contributor.authorGÜVEN, AHMET SAMİ
dc.contributor.authorSANCAKDAR, ENVER
dc.contributor.authorKAYA, ALİ
dc.contributor.authorUYSAL, ELİF BİLGE
dc.contributor.authorOFLAZ, MEHMET BURHAN
dc.contributor.authorBOLAT, FATİH
dc.contributor.authorKARAPINAR, HEKİM
dc.contributor.authorKOÇ, ELİF
dc.contributor.authorİÇAĞASIOĞLU, FÜSUN DİLARA
dc.contributor.institutionauthorİÇAĞASIOĞLU, DİLARA FÜSUN
dc.date.accessioned2020-10-29T14:56:47Z
dc.date.available2020-10-29T14:56:47Z
dc.date.issued2014-01-01T00:00:00Z
dc.description.abstractPurpose: The aim of this study was to assess the role of ABO blood groups in predicting disease severity and bleeding potential in children with Crimean-Congo hemorrhagic fever (CCHF). Methods: One hundred fifty-one hospitalized patients with CCHF were enrolled in this retrospective study. The patients were divided according to O- and non-O-(A, B and AB) blood groups (n=91 and n=60, respectively). They were also classified into two groups (severe and non-severe) based on disease severity (n=29 and n=122, respectively). Demographic characteristics, clinical findings, and hematologic and biochemical parameters of all patients were recorded on admission and discharge. Results: Although, in all cases, compared to the non-O blood group, the ratio of the blood group O was considerably higher (60% vs. 40%) and similarly so in severe cases (58.6% vs. 41.4%), this difference was not statistically significant (p>0.05). The aPTT at discharge and fever duration of the O-blood group were significantly higher than those of the non-O-blood group (p=0.042, p=0.034, respectively). The factor VIII level of the O-blood group was significantly lower than that of the non-O-blood group (p=0.040). Although the ratios of bleeding and severity were higher in the O-blood group compared to the other group, statistical significance was not reached (p>0.05). Conclusions: Consideration of the ABO blood group is important during diagnostic follow-up to assess the severity of CCHF. In clinical practice, pediatric CCHF patients with the O blood group need to be followed closely for tendency to bleed.
dc.identifier.citationGÜVEN A. S. , SANCAKDAR E., KAYA A., UYSAL E. B. , OFLAZ M. B. , BOLAT F., KARAPINAR H., KOÇ E., İÇAĞASIOĞLU F. D. , -Value of ABO blood group in predicting the severity of children with Crimean-Congo hemorrhagic fever-, INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, cilt.7, ss.416-420, 2014
dc.identifier.scopus84894563982
dc.identifier.urihttp://hdl.handle.net/20.500.12645/25522
dc.identifier.wosWOS:000333151800012
dc.titleValue of ABO blood group in predicting the severity of children with Crimean-Congo hemorrhagic fever
dc.typeArticle
dspace.entity.typePublication
local.avesis.id31a31297-7b14-4cdd-91f3-0e18389a9e04
local.publication.isinternational1
relation.isAuthorOfPublicationd6e0d341-df58-438f-bfac-96639f63d5d3
relation.isAuthorOfPublication.latestForDiscoveryd6e0d341-df58-438f-bfac-96639f63d5d3
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