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Does CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?

dc.contributor.authorOZCELIK, Hatice
dc.contributor.authorKAYAR, Yusuf
dc.contributor.authorDANALIOGLU, Ahmet
dc.contributor.authorARABACI, ELİF
dc.contributor.authorUysal, Omer
dc.contributor.authorYAKAR, Fatih
dc.contributor.authorKART, Levent
dc.contributor.institutionauthorARABACI, ELİF
dc.contributor.institutionauthorUYSAL, ÖMER
dc.date.accessioned2019-10-05T15:17:39Z
dc.date.available2019-10-05T15:17:39Z
dc.date.issued2017-03-01
dc.description.abstractObstructive sleep apnea (OSA) leads to upper respiratory tract obstruction, causing increased abdominal-gastric pressure and decreased lower esophageal sphincter (LES) pressure and thus gastroesophageal reflux (GER). Continuous positive airway pressure (CPAP) is known to be an effective method for OSA treatment, but its effect on GER is still controversial. There are a very few studies investigating CPAP and GER relationship and performed based on pre- and post-treatment objective parameters of GER in patients with OSA. The study investigated the effect of CPAP treatment in patients with moderate and severe OSA without GER complaints on pre- and post-treatment objective GER parameters. The study included 25 patients with respiratory disturbance indices > 15 without reflux symptoms who had undergone polysomnography at sleep laboratory. Age, sex, body mass index (BMI), waist, and neck circumference of the patients were documented. DeMeester score, LES pressure, and polysomnography parameters were evaluated pre- and post-CPAP. The results were statistically evaluated, and p value 0.05) was found comparing pre-CPAP and post-CPAP measurements. Objective criteria show that CPAP treatment does not cause reflux in patients with OSA. Unlike studies reported in the literature, this conclusion has been reached by pre- and post-CPAP assessments.
dc.identifier
dc.identifier.citationOZCELIK H., KAYAR Y., DANALIOGLU A., ARABACI E., Uysal O., YAKAR F., KART L., -Does CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?-, EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.274, ss.1223-1229, 2017
dc.identifier.doi10.1007/s00405-016-4116-0
dc.identifier.pubmed27334527
dc.identifier.scopus84975505838
dc.identifier.urihttps://hdl.handle.net/20.500.12645/5923
dc.identifier.wosWOS:000394350800005
dc.language.isoen
dc.titleDoes CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameVAN TIP DERGİSİ
local.avesis.id92c6f5af-4855-41bb-b604-d72a99fffdc8
local.avesis.response5793
local.publication.isinternational1
relation.isAuthorOfPublication8446f97e-fb2a-46e2-9da9-91dc2951e038
relation.isAuthorOfPublication19df24c5-c3e8-4158-8eed-717f885c608d
relation.isAuthorOfPublication.latestForDiscovery19df24c5-c3e8-4158-8eed-717f885c608d
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