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Phytochemical Screening, Antioxidant and Anticholinesterase Activity of Origanum amanum Post Endemic to Turkey

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dc.contributor.authorCarikci, Sema
dc.contributor.authorGÖREN, AHMET CEYHAN
dc.contributor.authorKilic, Turgut
dc.contributor.authorDirmenci, Tuncay
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2020-08-19T20:59:09Z
dc.date.available2020-08-19T20:59:09Z
dc.date.issued2020-01-01T00:00:00Z
dc.description.abstractThe phenolic and essential oil profiles and, antioxidant and anticholinesterase activities (AChE and BChE inhibitory activities) of Origanum amanum Post endemic to Turkey were investigated. The oil was obtained by applying hydrodistillation method and analyzed by GC-MS/MS. The plant was extracted with chloroform (C), acetone (Ac) and methanol (M). The extracts were analyzed through LC-MS/MS and the phenolic compounds were determined in quantitative amounts. Inhibition of lipid peroxidation, Cu2+ and DPPH scavenging and anticholinesterase activity of the extracts were analyzed. The main compounds of the essential oil of O. amanum were determined as cymene, carvacrol and gamma-terpinene. Rosmarinic, t-ferulic and caffeic acids were determined as the main compounds of the extracts. While the extracts did not inhibit AChE, Ac extract inhibited BChE moderately. Moreover, acetone and methanol extracts of O. amanum showed good antioxidant activity.
dc.description.sponsorshipTürkiye Bilimsel Ve Teknolojik Araştırma Kurumu ( Tübitak )
dc.identifier.citationCarikci S., GÖREN A. C. , Kilic T., Dirmenci T., -Phytochemical Screening, Antioxidant and Anticholinesterase Activity of Origanum amanum Post Endemic to Turkey-, ZEITSCHRIFT FUR ARZNEI- & GEWURZPFLANZEN, cilt.25, ss.4-8, 2020
dc.identifier.urihttp://hdl.handle.net/20.500.12645/18407
dc.identifier.wosWOS:000540874600002
dc.language.isoen
dc.titlePhytochemical Screening, Antioxidant and Anticholinesterase Activity of Origanum amanum Post Endemic to Turkey
dc.typeArticle
dspace.entity.typePublication
local.avesis.id0eed20b7-b149-445f-b90f-19336e08245d
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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