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Hipotiroidi Tedavisine Deneysel Alternatif Yöntem: Tiroid Dokusunun Kapsüle Edilmesi. Experimental Alternative Method for the Treatment of Hypothyroidism: Capsulation of the Thyroid Tissue.

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dc.contributor.authorYücesan, Emrah
dc.contributor.authorBaşoğlu, Harun
dc.contributor.authorÖzten Kandaş, Nur
dc.contributor.authorKanımdan, Ebru
dc.contributor.authorAkbaş, Fahri
dc.contributor.authorErsoy, Yeliz Emine
dc.contributor.authorAyşan, Erhan
dc.contributor.institutionauthorGÖNCÜ, BEYZA SERVET
dc.contributor.institutionauthorAKBAŞ, FAHRİ
dc.contributor.institutionauthorERSOY, YELIZ EMINE
dc.date.accessioned2020-01-29T20:59:11Z
dc.date.available2020-01-29T20:59:11Z
dc.date.issued2018-10-01T00:00:00Z
dc.description.abstractObjective: Hypothyroidism is a clinical condition that affects all age groups. Generally, lifelong medication is required for the treatment. Despite treatment, symptoms that are related to hormone insufficiency and side effects due to long-term medication can be seen. As an alternative approach, thyroid tissue transplantation may be useful, because of its potential to elevate the thyroid hormone levels and thus increase daily quality of life for the patients. Our aim in this study was to detect the in vitro optimal microencapsulation conditions for thyroid tissues with a biocompatible polymer to avoid immune rejection following transplantation. Material and Methods: Thyroid tissues were isolated mechanically, and followed-up in two groups; tissue and capsulated tissue culture. In-vitro capsule formation and morphology were screened using brightfield microscopy and T3 and T4 levels were evaluated biochemically throughout 60 days. Results: T3 and T4 levels were screened from collected medium samples at day 3., 9., 12., 15., 30., 45., 60.. In capsuled tissues T3 level was detected higher than the non-capsuled and negative control tissues from day 15. However, T4 level was stable for 60 days.en
dc.identifier.citationYücesan E., Göncü B., Başoğlu H., Özten Kandaş N., Kanımdan E., Akbaş F., Ersoy Y. E. , Ayşan E., -Hipotiroidi Tedavisine Deneysel Alternatif Yöntem: Tiroid Dokusunun Kapsüle Edilmesi. Experimental Alternative Method for the Treatment of Hypothyroidism: Capsulation of the Thyroid Tissue. -, Akdeniz Tıp Dergisi / Akdeniz Medical Journal , no.1017954, ss.1122, 2018
dc.identifier.urihttps://openaccess.bezmialem.edu.tr/handle/20.500.12645/14010
dc.language.isotr
dc.titleHipotiroidi Tedavisine Deneysel Alternatif Yöntem: Tiroid Dokusunun Kapsüle Edilmesi. Experimental Alternative Method for the Treatment of Hypothyroidism: Capsulation of the Thyroid Tissue.
dc.typeArticle
dspace.entity.typePublication
local.avesis.id27546830-5bed-4a4b-9b77-5b3f2d744aa0
local.publication.isinternational0
relation.isAuthorOfPublication2f62fb6f-8415-4dca-9a79-54a3d131a08a
relation.isAuthorOfPublication1da13c4a-283a-47d4-a763-1c242fde6919
relation.isAuthorOfPublication29a098c6-acc4-4e05-af39-eeffbc7be778
relation.isAuthorOfPublication.latestForDiscovery1da13c4a-283a-47d4-a763-1c242fde6919
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