Publication:
Lateralized Differences in Olfactory Function and Olfactory Bulb Volume Relate to Nasal Septum Deviation

dc.contributor.authorALTUNDAG, Aytug
dc.contributor.authorSALIHOGLU, Murat
dc.contributor.authorTEKELI, Hakan
dc.contributor.authorSaglam, MUZAFFER
dc.contributor.authorCayonu, Melih
dc.contributor.authorHUMMEL, Thomas
dc.contributor.institutionauthorSAĞLAM, MUZAFFER
dc.date.accessioned2020-10-29T21:16:25Z
dc.date.available2020-10-29T21:16:25Z
dc.date.issued2014-03-01T00:00:00Z
dc.description.abstractOne of the most common reasons for partial nasal obstruction is nasal septal deviation (NSD). The effect of a partial lateralized nasal obstruction on olfactory bulb (OB) volume remains unclear. Thus, the aim of this study was to investigate the side differences in olfactory function and OB in patients with serious NSD. Sixty-five volunteers were included: 22 patients with serious right NSD and 43 patients with left NSD. The patients- mean age was 22 years. All participants received volumetric magnetic resonance imaging scans of the entire brain and detailed lateralized olfactory tests. The majority of the patients exhibited an overall decreased olfactory function (as judged for the better nostril: functional anosmia in 3%, hyposmia in 72%, normosmia in 25%), which seems to be mostly due to the overall severe changes in nasal anatomy. As expected, olfactory function was significantly lower at the narrower side as indicated for odor thresholds, odor discrimination, and odor identification (P <= 0.005). When correlating relative scores and volumes (wider minus narrower side), a significantly positive correlation between the relative measures emerged for OB volume and odor identification, odor discrimination, and odor thresholds. Our study clearly highlights that septal deviation results in decreased olfactory function at the narrower side.
dc.identifier.citationALTUNDAG A., SALIHOGLU M., TEKELI H., Saglam M., Cayonu M., HUMMEL T., -Lateralized Differences in Olfactory Function and Olfactory Bulb Volume Relate to Nasal Septum Deviation-, JOURNAL OF CRANIOFACIAL SURGERY, cilt.25, ss.359-362, 2014
dc.identifier.doi10.1097/scs.0000000000000617
dc.identifier.scopus84897057418
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26227
dc.identifier.wosWOS:000335381800052
dc.titleLateralized Differences in Olfactory Function and Olfactory Bulb Volume Relate to Nasal Septum Deviation
dc.typeArticle
dspace.entity.typePublication
local.avesis.id80fb2b83-442d-4732-afbd-426acc289a0d
local.publication.isinternational1
relation.isAuthorOfPublication14122938-a68a-4dce-ad4f-0e7642206d62
relation.isAuthorOfPublication.latestForDiscovery14122938-a68a-4dce-ad4f-0e7642206d62
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