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False positivity of magnetic resonance imaging under the effect of granulocyte-colony stimulating factor in a child with leukemia

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dc.contributor.authorÇAKIR, FATMA BETÜL
dc.contributor.authorBaysal, Begümhan
dc.contributor.authorDoğan, Öner
dc.contributor.institutionauthorÇAKIR, FATMA BETÜL
dc.date.accessioned2019-10-05T14:35:29Z
dc.date.available2019-10-05T14:35:29Z
dc.date.issued2013-06-01
dc.description.abstractGranulocyte-colony stimulating factor (G-CSF) increases the proliferation and maturation of committed polymorphonuclear leukocyte precursors, as well as the function of mature polymorphonuclear leukocytes. It has previously been shown in pediatric patients that G-CSF induces reconversion of fatty bone marrow to hematopoietic bone marrow in the pelvis and lower extremities that is detectable by magnetic resonance imaging (MRI). Here, we report a 13-year-old Burkitt leukemia patient with bone pain while he was in remission. He was on G-CSF after cessation of high-dose and low-dose cytarabine chemotherapy. He was suspected to have a leukemia relapse. Pelvic MRI was consistent with leukemic infiltration. However, the pathology of bone marrow biopsy resulted in normal findings. Thus it was suggested that concurrent administration of G-CSF could be the causative agent for both bone pain and false-positive MRI findings. The control MRI after interruption of G-CSF revealed normal findings. In conclusion, radiologists should be informed about the type of therapy, including G-CSF administration, in order to overcome misinterpretation of bone marrow MRI.en
dc.identifier
dc.identifier.citationÇAKIR F. B. , Baysal B., Doğan Ö., -False positivity of magnetic resonance imaging under the effect of granulocyte-colony stimulating factor in a child with leukemia-, WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, cilt.17, ss.334-336, 2013
dc.identifier.pubmed24596527
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4222
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleFalse positivity of magnetic resonance imaging under the effect of granulocyte-colony stimulating factor in a child with leukemia
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
local.avesis.id667875fd-8144-41e0-946b-7fa830a4041f
local.avesis.response4092
relation.isAuthorOfPublication4b01ee0e-c087-44d4-9581-4d73032d078e
relation.isAuthorOfPublication.latestForDiscovery4b01ee0e-c087-44d4-9581-4d73032d078e
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