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Inhibition of iNOS Induction and NF-kappa B Activation by Taste Compounds from the Edible Mushroom Tricholoma caligatum (Viv.) Ricken

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dc.contributor.authorErol, EBRU
dc.contributor.authorAli, Zulfiqar
dc.contributor.authorOzturk, Mehmet
dc.contributor.authorKhan, Shabana
dc.contributor.authorKhan, Ikhlas A.
dc.contributor.institutionauthorEROL, EBRU
dc.date.accessioned2021-06-07T20:59:07Z
dc.date.available2021-06-07T20:59:07Z
dc.date.issued2020-01-01T00:00:00Z
dc.description.abstractTricholoma caligatum (Viv.) Ricken is an edible mushroom that belongs to matsutake group. The first chemical investigation of the three different extracts of Tricholoma caligatum resulted in two new compounds, 8-demethoxylascivol (1) and 8-epi-lascivol (2) and six known compounds, lascivol (3), trametenolic acid (4), ergosterol (5), ergosterol peroxide (6), 5 alpha, 6 alpha-epoxyergosterol (7), and cerebroside B (8). Their structures were elucidated by spectroscopic analyses including 1D and 2D NMR data. The biological activities of all the compounds were evaluated toward multiple targets related to inflammation and metabolic disorder such as NF-kappa B, iNOS and ROS. The findings of this study reveal that the edible mushroom Tricholoma caligatum could be a potential source for anti-inflammatory bioactive metabolites.
dc.identifier.citationErol E., Ali Z., Ozturk M., Khan S., Khan I. A. , -Inhibition of iNOS Induction and NF-kappa B Activation by Taste Compounds from the Edible Mushroom Tricholoma caligatum (Viv.) Ricken-, RECORDS OF NATURAL PRODUCTS, cilt.14, sa.1, ss.77-82, 2020
dc.identifier.doi10.25135/rnp.139.19.04.1263
dc.identifier.scopus85073572727
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28957
dc.identifier.wosWOS:000485964000009
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleInhibition of iNOS Induction and NF-kappa B Activation by Taste Compounds from the Edible Mushroom Tricholoma caligatum (Viv.) Ricken
dc.typeArticle
dspace.entity.typePublication
local.avesis.id02b560f2-89dd-4333-906d-ea8bee36bfc6
local.publication.isinternational1
relation.isAuthorOfPublication4b88c10c-1317-49d6-9594-59ecd8583cb6
relation.isAuthorOfPublication.latestForDiscovery4b88c10c-1317-49d6-9594-59ecd8583cb6
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