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Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study

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dc.contributor.authorUysal M.
dc.contributor.authorSaglam S.
dc.contributor.authorBeypınar İ.
dc.contributor.authorSaglam E. K.
dc.contributor.authorMammadov E.
dc.contributor.authorOcak B.
dc.contributor.authorAybi O.
dc.contributor.authorArıkan R.
dc.contributor.authorERGEN Ş. A.
dc.contributor.authorGursoy P.
dc.contributor.authoret al.
dc.date.accessioned2026-01-07T21:36:41Z
dc.date.issued2025-01-01
dc.description.abstractThe goal of this study was to look at the long-term survival outcomes and clinical characteristics of stage II/III locally advanced rectal cancer (LARC) patients who acquired pathological complete response (pCR) following neoadjuvant chemoradiotherapy (NCRT). The clinicopathological characteristics and treatment details of 277 LARC patients with pCR, relapse-free survival (RFS), overall survival (OS), and locoregional and systemic recurrence rates, were assessed. The 5-year RFS and OS rates were 85.6% and 90.9%. The rates of local and systemic recurrence were 3.6% and 7.9%. Our study confirmed the favorable results in survival in patients with LARC who achieved pCR.
dc.identifier.citationUysal M., Saglam S., Beypınar İ., Saglam E. K., Mammadov E., Ocak B., Aybi O., Arıkan R., ERGEN Ş. A., Gursoy P., et al., "Long-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study", Cancer Investigation, 2025
dc.identifier.doi10.1080/07357907.2025.2595536
dc.identifier.issn0735-7907
dc.identifier.pubmed41347635
dc.identifier.scopus105024909531
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105024909531&origin=inward
dc.identifier.urihttps://hdl.handle.net/20.500.12645/41572
dc.identifier.wosWOS:001631349200001
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectOnkoloji
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectInternal Diseases
dc.subjectOncology
dc.subjectLife Sciences
dc.subjectMolecular Biology and Genetics
dc.subjectCytogenetic
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectKlinik Tıp (Med)
dc.subjectYaşam Bilimleri (Life)
dc.subjectKlinik Tıp
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectClinical Medicine (Med)
dc.subjectLife Sciences (Life)
dc.subjectClinical Medicine
dc.subjectMolecular Biology & Genetics
dc.subjectBiochemistry & Molecular Biology
dc.subjectKanser Araştırmaları
dc.subjectCancer Research
dc.subjectDisease-free survival
dc.subjectLocal advanced rectal cancer
dc.subjectLocal recurrence
dc.subjectNeoadjuvant chemoradiation
dc.subjectOverall survival
dc.subjectPathological complete response
dc.subjectSurgical outcome
dc.titleLong-Term Oncological Outcomes for Locally Advanced Rectal Cancer Patients with Pathological Complete Response After Neoadjuvant Chemoradiotherapy: A Turkish Oncology Group Study
dc.typearticle
dspace.entity.typePublication
local.avesis.ida773bbfb-c690-4946-ab85-aee5194d8a5f

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