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Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases

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dc.contributor.authorTÜREL, Özden
dc.contributor.authorKazanci, Selcen
dc.contributor.authorGonen, Ismail
dc.contributor.authorAydogmus, Cigdem
dc.contributor.authorKaraoglan, Emel
dc.contributor.authorSiraneci, Rengin
dc.contributor.institutionauthorTÜREL, ÖZDEN
dc.date.accessioned2020-10-22T18:36:47Z
dc.date.available2020-10-22T18:36:47Z
dc.date.issued2016-01-01T00:00:00Z
dc.description.abstractBackground. Tuberculosis (TB) still remains a growing public health problem globally. TB in children is often diagnosed clinically. Methods. We conducted a retrospective chart review of children with TB from November 2004 through December 2010 to determine the appropriateness of using contact history and diagnostic testing. Results. A total of 250 children with TB were identified. One hundred and sixty-two children had only pulmonary disease while 39 had features of both extrapulmonary and pulmonary TB. Mean age was 7.8 years. Thirty-six patients had known contacts. The index case/cases were first-degree relatives in 75%. Sixteen patients who were symptomless were yielded by contact investigation of newly identified TB cases. Tuberculin skin test positivity was 53.3%. Acid-fast bacilli smear positivity was 13.1%, and culture positivity was 18.7%. Twenty-six patients had histopathology of nonrespiratory specimens (lymph nodes and other tissues) showing granulomatous inflammation and caseous necrosis consistent with TB. Conclusions. Presence of contact history directed us to search for TB in children with nonspecific symptoms even if physical examinations were normal. Some children who were close contacts to TB cases were identified to have TB before development of symptoms.
dc.identifier.citationTÜREL Ö., Kazanci S., Gonen I., Aydogmus C., Karaoglan E., Siraneci R., -Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases-, BIOMED RESEARCH INTERNATIONAL, cilt.2016, 2016
dc.identifier.doi10.1155/2016/6896279
dc.identifier.pubmed27298827
dc.identifier.scopus84973402239
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24255
dc.identifier.wosWOS:000376917300001
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPaediatric Tuberculosis
dc.titlePaediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases
dc.typeArticle
dspace.entity.typePublication
local.avesis.id99c5d884-1c95-49d2-adab-30c1cf0d742f
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
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