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A New Parameter Predicting Chronic Total Occlusion of Coronary Arteries: Platelet Distribution Width

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dc.contributor.authorVatankulu, Mehmet Akif
dc.contributor.authorSonmez, Osman
dc.contributor.authorErtas, Gokhan
dc.contributor.authorBACAKSIZ, AHMET
dc.contributor.authorTurfan, Murat
dc.contributor.authorErdogan, Ercan
dc.contributor.authorTasal, Abdurrahman
dc.contributor.authorKul, Seref
dc.contributor.authorUyarel, Huseyin
dc.contributor.authorGoktekin, Omer
dc.contributor.institutionauthorBACAKSIZ, AHMET
dc.date.accessioned2020-10-22T19:24:01Z
dc.date.available2020-10-22T19:24:01Z
dc.date.issued2014-01-01T00:00:00Z
dc.description.abstractPlatelet distribution width (PDW) measures the variability in platelet size and is a marker of platelet activation. We investigated whether PDW is associated with the extent of coronary artery disease (CAD) and coronary total occlusions (CTOs). We studied 162 patients: 108 had a coronary lesion with a diameter stenosis of 50%, the CAD(+) group, and 54 patients had normal coronary anatomy, the CAD(-) group. The CAD(+) group was subdivided into CAD(+) CTO(+) and CAD(+) CTO(-) groups. Among patients with CAD, the CTO(+) group had a significantly greater PDW (%) than the CTO(-) group (16.9 +/- 2.8, 15.4 +/- 3.0, and 15.4 +/- 1.9, respectively; P = .008). In a receiver-operating characteristic analysis, a PDW cut point of 15.7% was identified in patients with CTO(+) (area under curve = 0.64, 95% confidence interval 0.54-0.75). A PDW value of more than 15.7% demonstrated a sensitivity of 64% and a specificity of 66%. The PDW is a simple platelet index that may predict the presence of CTO.
dc.identifier.citationVatankulu M. A. , Sonmez O., Ertas G., BACAKSIZ A., Turfan M., Erdogan E., Tasal A., Kul S., Uyarel H., Goktekin O., -A New Parameter Predicting Chronic Total Occlusion of Coronary Arteries: Platelet Distribution Width-, ANGIOLOGY, cilt.65, ss.60-64, 2014
dc.identifier.doi10.1177/0003319713486339
dc.identifier.pubmed23636855
dc.identifier.scopus84888599075
dc.identifier.urihttp://hdl.handle.net/20.500.12645/24437
dc.identifier.wosWOS:000327294000012
dc.titleA New Parameter Predicting Chronic Total Occlusion of Coronary Arteries: Platelet Distribution Width
dc.typeArticle
dspace.entity.typePublication
local.avesis.idb552a6e2-e95f-4e00-9019-2969e484444e
local.publication.isinternational1
relation.isAuthorOfPublicationaf75b431-3b28-42b6-93a9-357a5d965904
relation.isAuthorOfPublication.latestForDiscoveryaf75b431-3b28-42b6-93a9-357a5d965904
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