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Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis

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dc.contributor.authorKiziltoprak, Hasan
dc.contributor.authorKoc, Mustafa
dc.contributor.authorTekin, Kemal
dc.contributor.authorHekimoglu, Rumeysa
dc.contributor.authorInanc, Merve
dc.contributor.authorYilmaz, Aslihan Arasli
dc.contributor.authorElmaogullari, Selin
dc.contributor.authorAycan, Zehra
dc.contributor.institutionauthorHEKİMOĞLU, EMİNE RÜMEYSA
dc.date.accessioned2019-12-31T20:59:16Z
dc.date.available2019-12-31T20:59:16Z
dc.date.issued2019-08-17
dc.description.abstractPurpose: To evaluate the ocular surface characteristics based on Schirmer-s test, tear break-up time (TBUT), and conjunctival impression cytology (CIC) in children with Hashimoto-s thyroiditis (HT). Methods: This study included 51 children with HT and 53 control subjects. The ocular surface characteristics of participants were assessed via Schirmer-s test, TBUT, and CIC. Conjunctival samples were examined cytologically according to the Nelson grading system. Results: Schirmer-s and TBUT results were significantly lower in HT group (p < .05). All samples in both the study and control groups were evaluated as grade 0 according to the Nelson classification (p = .841), however, goblet cell density (GCD) was significantly lower in HT group (p = .001). Schirmer test results were significantly associated with the duration of HT (p = .025, r = -0.311). Conclusion: Hashimoto-s thyroiditis without any ocular complaints may cause ocular surface changes with TBUT and Schirmer-s. Although CIC analysis showed similar grading results, GCD was significantly decreased in HT group.
dc.identifier.citationKiziltoprak H., Koc M., Tekin K., Hekimoglu R., Inanc M., Yilmaz A. A. , Elmaogullari S., Aycan Z., -Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis-, OCULAR IMMUNOLOGY AND INFLAMMATION, 2019
dc.identifier.pubmed31414613
dc.identifier.urihttps://hdl.handle.net/20.500.12645/11143
dc.titleLocal Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id702202df-457d-4692-a44e-f6da5f325f0f
relation.isAuthorOfPublication47739f84-bd54-4c7c-9a22-f2d415732282
relation.isAuthorOfPublication.latestForDiscovery47739f84-bd54-4c7c-9a22-f2d415732282
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