Publication:
Oxidative and Inflammatory Parameters in Children and Adolescents With ADHD.

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dc.contributor.authorKoç, Sümeyye
dc.contributor.authorGüler, Eray Metin
dc.contributor.authorDerin, Songül
dc.contributor.authorGültekin, Fatih
dc.contributor.authorAktaş, Selman
dc.date.accessioned2023-05-16T14:39:51Z
dc.date.available2023-05-16T14:39:51Z
dc.date.issued2023-03-05T21:00:00Z
dc.description.abstractThis study aims that oxidative stress and inflammation status in children and adolescents with attention deficit hyperactivity disorder (ADHD) compared to their healthy peers.
dc.description.abstractThirty ADHD and healthy controls were included in this study. ADHD diagnosis according to the DSM-V and Conners' teacher and parent rating scale by a structured psychiatric interview. Total oxidant status (TOS), total antioxidant status (TAS), and total and native thiol levels were determined using photometric methods. Presepsin, Interleukin (IL) 1-ß, IL-6, and Tumor Necrosis Factor-alpha (TNF-α) levels were measured with commercial ELISA kits.
dc.description.abstractWe showed that TOS and oxidative stress index were significantly higher in the ADHD group, and TAS was lower than in the control group (<.001). Similarly, IL1-ß, IL-6, and TNF-α levels were statistically higher in the ADHD group. Backward LR regression analysis reveals that TOS and IL-6 predicted ADHD.
dc.description.abstractTOS and IL-6 levels may play a role in the pathogenesis of ADHD.
dc.identifier.pubmed36879528
dc.identifier.urihttps://hdl.handle.net/20.500.12645/37843
dc.language.isoen
dc.subjectIL-6
dc.subjectantioxidant
dc.subjectattention deficit hyperactivity disorder
dc.subjectinflammation
dc.subjectoxidative stress
dc.titleOxidative and Inflammatory Parameters in Children and Adolescents With ADHD.
dspace.entity.typePublication
local.indexed.atPubMed

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